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  1. Organ-specific, adult stem cells are essential for organ-homeostasis and tissue repair and regeneration. The formation of such stem cells during vertebrate development remains to be investigated. Frog metamorp...

    Authors: Nga Luu, Luan Wen, Liezhen Fu, Kenta Fujimoto, Yun-Bo Shi and Guihong Sun
    Citation: Cell & Bioscience 2013 3:43
    Content type: Research Published on:

  3. Adult stem cells maintain tissue homeostasis by their ability to both self-renew and differentiate to distinct cell types. Multiple signaling pathways have been shown to play essential roles as extrinsic cues ...

    Authors: Lama Tarayrah and Xin Chen
    Citation: Cell & Bioscience 2013 3:41
    Content type: Review Published on:

  8. Our previous research demonstrated that one subcutaneous injection of 17-Dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) 24 hours (h) before irradiation (8.75 Gy) increased mouse survival by 75%. Ho...

    Authors: Xinyue Lu, Dilber Nurmemet, David L Bolduc, Thomas B Elliott and Juliann G Kiang
    Citation: Cell & Bioscience 2013 3:36
    Content type: Research Published on:

  9. Autophagy serves as a dynamic degradation and recycling system that provides biological materials and energy in response to stress. The role of autophagy in tumor development is complex. Various studies sugges...

    Authors: Kai Sun, Weijie Deng, Shanshan Zhang, Ning Cai, Shufan Jiao, Jianrui Song and Lixin Wei
    Citation: Cell & Bioscience 2013 3:35
    Content type: Review Published on:

  13. The Hippo signaling pathway has emerged as a critical regulator for organ size control. The serine/threonine protein kinases Mst1 and Mst2, mammalian homologs of the Hippo kinase from Drosophila, play the cent...

    Authors: Funiu Qin, Jing Tian, Dawang Zhou and Lanfen Chen
    Citation: Cell & Bioscience 2013 3:31
    Content type: Review Published on:

  15. Merkel cell polyomavirus (MCPyV) is a DNA virus expressing transcripts similar to the large T (LT) and small T (ST) transcripts of SV40, which has been implicated in the pathogenesis of Merkel cell carcinoma (...

    Authors: Bianca Gomez, Liangmei He, Ya Chea Tsai, T-C Wu, Raphael P Viscidi and Chien-Fu Hung
    Citation: Cell & Bioscience 2013 3:29
    Content type: Research Published on:

  16. The previous investigation demonstrated the radioprotective efficacy of peptides isolated from the venom of Buthus Martti Karsch. In this study, the effect of isolated scorpion venom peptide II (SVPII) on irradia...

    Authors: Yifang Qiu, Liyuan Jiang, Caixia Wang, Yan Wang, Ting Li, Baiqian Xing, Meixun Zhou, Tianhan Kong and Weihua Dong
    Citation: Cell & Bioscience 2013 3:28
    Content type: Research Published on:

  17. Hemicentin has come a long way from when it was first identified in C. elegans as him-4 (High incidence of males). The protein is now a recognized player in maintaining the architectural integrity of vertebrate t...

    Authors: Xuehong Xu, MengMeng Xu, Xin Zhou, Odell B Jones, Edward Moharomd, Yuexin Pan, Guifang Yan, Donald D Anthony and Williams B Isaacs
    Citation: Cell & Bioscience 2013 3:27
    Content type: Review Published on:

  18. Hepatic ischemia/reperfusion is a multi-factorial process which causes liver injury. It is reported that ischemia alone is sufficient to induce liver injury. Nutrient deprivation is a crucial factor impacting ...

    Authors: Kai Sun, Xuqin Xie, Yan Liu, Zhipeng Han, Xue Zhao, Ning Cai, Shanshan Zhang, Jianrui Song and Lixin Wei
    Citation: Cell & Bioscience 2013 3:26
    Content type: Research Published on:

  23. Transcription activator-like effector nucleases (TALENs) are novel engineered DNA nucleases, and have been proven to be effective for gene specific targeting in various species. Recently we reported gene disru...

    Authors: Yong Lei, Xiaogang Guo, Yi Deng, Yonglong Chen and Hui Zhao
    Citation: Cell & Bioscience 2013 3:21
    Content type: Review Published on:

  26. The mammalian intestine has long been used as a model to study organ-specific adult stem cells, which are essential for organ repair and tissue regeneration throughout adult life. The establishment of the inte...

    Authors: Takashi Hasebe, Liezhen Fu, Thomas C Miller, Yu Zhang, Yun-Bo Shi and Atsuko Ishizuya-Oka
    Citation: Cell & Bioscience 2013 3:18
    Content type: Research Published on:

  28. Metastasis-associated in colon cancer-1 (MACC1) was first identified as a transcriptional activator for proto-oncogene c-MET expression, and its overexpression is frequently associated with metastatic progress...

    Authors: Yongbo Huang, Huizhong Zhang, Junchao Cai, Lishan Fang, Jueheng Wu, Caisheng Ye, Xun Zhu and Mengfeng Li
    Citation: Cell & Bioscience 2013 3:16
    Content type: Research Published on:

  35. As a hallmark of tumor cells, metabolic alterations play a critical role in tumor development and could be targeted for tumor therapy. Tumor suppressor p53 plays a central role in tumor prevention. As a transc...

    Authors: Yingjian Liang, Juan Liu and Zhaohui Feng
    Citation: Cell & Bioscience 2013 3:9
    Content type: Review Published on:

  39. The discovery of tissue reparative and immunosuppressive abilities of mesenchymal stem cells (MSCs) has drawn more attention to tumor microenvironment and its role in providing the soil for the tumor cell grow...

    Authors: Xue Yang, Jing Hou, Zhipeng Han, Ying Wang, Chong Hao, Lixin Wei and Yufang Shi
    Citation: Cell & Bioscience 2013 3:5
    Content type: Review Published on:

  40. TGF-β1 is an immunoregulatory cytokine that regulates immune cell proliferation, survival, differentiation, and migration. Compelling evidence has demonstrated a strong association between the immune and skele...

    Authors: Shimpei Kasagi and Wanjun Chen
    Citation: Cell & Bioscience 2013 3:4
    Content type: Review Published on:

  41. The editors of Cell & Bioscience would like to thank all the reviewers who contributed to the journal in Volume 2 (2012).

    Authors: Yun-Bo Shi
    Citation: Cell & Bioscience 2013 3:3
    Content type: Reviewer acknowledgement Published on:

  42. Following the successful cloning of receptor for SARS coronavirus a few years ago, Dr. Wenhui Li and colleagues raised attention again by publishing a possible receptor for hepatitis B virus in eLife. We will bri...

    Authors: Pei-Jer Chen and T-C Wu
    Citation: Cell & Bioscience 2013 3:2
    Content type: Commentary Published on:

  43. The nucleosome remodeling and histone deacetylase complex (Mi2/NRD/NuRD/NURD) has a broad role in regulation of transcription, DNA repair and cell cycle. Previous studies have revealed a specific interaction b...

    Authors: Meng Wu, Lina Wang, Qian Li, Jiwen Li, Jun Qin and Jiemin Wong
    Citation: Cell & Bioscience 2013 3:1
    Content type: Research Published on:

    The Erratum to this article has been published in Cell & Bioscience 2013 3:12

  44. Rheumatoid arthritis (RA) is a chronic autoimmune-disease of unknown origin that primarily affects the joints and ultimately leads to their destruction. Growing evidence suggests that synvovial fibroblasts pla...

    Authors: Daniel P Heruth, Margaret Gibson, Dmitry N Grigoryev, Li Qin Zhang and Shui Qing Ye
    Citation: Cell & Bioscience 2012 2:43
    Content type: Research Published on:

  45. Thyroid hormone (T3) plays diverse roles in adult organ function and during vertebrate development. The most important stage of mammalian development affected by T3 is the perinatal period when plasma T3 level...

    Authors: Yun-Bo Shi, Kazuo Matsuura, Kenta Fujimoto, Luan Wen and Liezhen Fu
    Citation: Cell & Bioscience 2012 2:42
    Content type: Review Published on:

  46. Tombusvirus P19 is a protein encoded by tomato bushy stunt virus and related tombusviruses. Earlier studies have demonstrated that P19 is an RNA silencing suppressor (RSS) in plant cells. However, it has not b...

    Authors: Xiang Liu, Laurent Houzet and Kuan-Teh Jeang
    Citation: Cell & Bioscience 2012 2:41
    Content type: Research Published on:

  47. NF-E2-related factor 2 (NRF2) regulates a battery of antioxidative and phase II drug metabolizing/detoxifying genes through binding to the antioxidant response elements (ARE). NRF2-ARE signaling plays a central r...

    Authors: Ying Huang, Wenge Li and Ah-Ng Tony Kong
    Citation: Cell & Bioscience 2012 2:40
    Content type: Research Published on:

  48. Toxin-antitoxin (TA) systems are commonly found in bacteria and Archaea, and it is the most common mechanism involved in bacterial programmed cell death or apoptosis. Recently, MazF, the toxin component of the...

    Authors: Xianghe Yan, Joshua B Gurtler, Pina M Fratamico, Jing Hu and Vijay K Juneja
    Citation: Cell & Bioscience 2012 2:39
    Content type: Research Published on:
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  • ISSN: 2045-3701 (electronic)

Cell & Bioscience

ISSN: 2045-3701

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