Skip to main content

Articles

Page 1 of 20

  1. A variety of neurons in hypothalamus undergo a complicated regulation on transcription activity of multiple genes for hypothalamic–pituitary–gonadal axis activation during pubertal development. Identification ...

    Authors: Shasha Zhou, Shaolian Zang, Yanping Hu, Yifen Shen, Hua Li, Wenlian Chen, Pin Li and Yihang Shen

    Citation: Cell & Bioscience 2022 12:8

    Content type: Research

    Published on:

  2. One of coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused coronavirus disease 2019 (COVID-19) pandemic and threatened worldwide. However, therapy for COVID-19 has rarely been...

    Authors: Sang R. Lee, Jeong Yeon Roh, Jihoon Ryu, Hyun-Jin Shin and Eui-Ju Hong

    Citation: Cell & Bioscience 2022 12:7

    Content type: Research

    Published on:

  3. Ranaviruses (family Iridoviridae) are promiscuous pathogens that can infect across species barriers in poikilotherms and can replicate in amphibian and fish cells and even in cultured mammalian cells. However, as...

    Authors: Fei Ke, Xue-Dong Yu, Zi-Hao Wang, Jian-Fang Gui and Qi-Ya Zhang

    Citation: Cell & Bioscience 2022 12:6

    Content type: Research

    Published on:

  4. During male meiosis, the Y chromosome can form perfect pairing with the X chromosome. However, it is unclear whether mammalian Female germline stem cells (FGSCs) without a Y chromosome can transdifferentiate i...

    Authors: Xiaopeng Hu, Hu Wang, Geng. G. Tian, Changliang Hou, Bo Xu, Xinyan Zhao, Yongqiang Zhao, Qian Fang, Xinyue Li, Lin He, Xuejin Chen, Shangang Li and Ji Wu

    Citation: Cell & Bioscience 2022 12:5

    Content type: Research

    Published on:

  5. Although sex hormones play a key role in sex differences in susceptibility, severity, outcomes, and response to therapy of different diseases, sex chromosomes are also increasingly recognized as an important f...

    Authors: Raheleh Heydari, Zohreh Jangravi, Samaneh Maleknia, Mehrshad Seresht-Ahmadi, Zahra Bahari, Ghasem Hosseini Salekdeh and Anna Meyfour

    Citation: Cell & Bioscience 2022 12:4

    Content type: Review

    Published on:

  6. Neonates possess an immature and plastic immune system, which is a major cause of some diseases in newborns. Necrotizing enterocolitis (NEC) is a severe and devastating intestinal disease that typically affect...

    Authors: Xiuhao Zhao, Wenhua Liang, Yonghui Wang, Ruirong Yi, Lingjie Luo, Weifang Wang, Nannan Sun, Mingcheng Yu, Weijue Xu, Qingfeng Sheng, Li Lu, Jianfeng Pang, Zhibao Lv and Feng Wang

    Citation: Cell & Bioscience 2022 12:3

    Content type: Research

    Published on:

  7. Oxidative stress is mainly caused by intracellular reactive oxygen species (ROS) production, which is highly associated with normal physiological homeostasis and the pathogenesis of diseases, particularly ocul...

    Authors: Kun-Che Chang, Pei-Feng Liu, Chia-Hsuan Chang, Ying-Cheng Lin, Yen-Ju Chen and Chih-Wen Shu

    Citation: Cell & Bioscience 2022 12:1

    Content type: Review

    Published on:

  8. Anoctamin 5 (ANO5) is a membrane protein belonging to the TMEM16/Anoctamin family and its deficiency leads to the development of limb girdle muscular dystrophy R12 (LGMDR12). However, little has been known abo...

    Authors: Haiwen Li, Li Xu, Yandi Gao, Yuanbojiao Zuo, Zuocheng Yang, Lingling Zhao, Zhiheng Chen, Shuliang Guo and Renzhi Han

    Citation: Cell & Bioscience 2021 11:222

    Content type: Research

    Published on:

  9. Ferroptosis is unique among different types of regulated cell death and closely related to organ injury. Whether ferroptosis occurs in sepsis-associated acute kidney injury (SA-AKI) is not clear. Nuclear facto...

    Authors: Ji Xiao, Qian Yang, Ye’an Zhang, Haoran Xu, Yang Ye, Linchao Li, Yi Yang and Shengwei Jin

    Citation: Cell & Bioscience 2021 11:221

    Content type: Research

    Published on:

  10. Although multiple studies have demonstrated a role for exosomes during virus infections, our understanding of the mechanisms by which exosome exchange regulates immune response during viral infections and affe...

    Authors: Farhang Alem, Adeyemi A. Olanrewaju, Samson Omole, Heather E. Hobbs, Noor Ahsan, Graham Matulis, Christine A. Brantner, Weidong Zhou, Emanuel F. Petricoin, Lance A. Liotta, Massimo Caputi, Sina Bavari, Yuntao Wu, Fatah Kashanchi and Ramin M. Hakami

    Citation: Cell & Bioscience 2021 11:220

    Content type: Research

    Published on:

  11. Since the demonstration of its involvement in cell proliferation, the eukaryotic initiation factor 5A (eIF5A) has been studied principally in relation to the development and progression of cancers in which the...

    Authors: Michel Tauc, Marc Cougnon, Romain Carcy, Nicolas Melis, Thierry Hauet, Luc Pellerin, Nicolas Blondeau and Didier F. Pisani

    Citation: Cell & Bioscience 2021 11:219

    Content type: Review

    Published on:

  12. Controversy over the benefits of antioxidants supplements in cancers persists for long. Using hepatocellular carcinoma (HCC) as a model, we investigated the effects of exogenous antioxidants N-acetylcysteine (NAC...

    Authors: Vanilla Xin Zhang, Karen Man-Fong Sze, Lo-Kong Chan, Daniel Wai-Hung Ho, Yu-Man Tsui, Yung-Tuen Chiu, Eva Lee, Abdullah Husain, Hongyang Huang, Lu Tian, Carmen Chak-Lui Wong and Irene Oi-Lin Ng

    Citation: Cell & Bioscience 2021 11:217

    Content type: Research

    Published on:

  13. Macrophages are a central immune component in various types of in vitro human organoid systems to recapitulate normal and pathological development. However, to date, generation of human alveolar organoids (AOs...

    Authors: Hye-Ryeon Heo and Seok-Ho Hong

    Citation: Cell & Bioscience 2021 11:216

    Content type: Letter to the Editor

    Published on:

  14. In February 2020, we highlighted the top nine important research questions on SARS-CoV-2 and COVID-19 concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccin...

    Authors: Kit-San Yuen, Zi-Wei Ye, Sin-Yee Fung, Pak-Hin Hinson Cheung, Chi-Ping Chan and Dong-Yan Jin

    Citation: Cell & Bioscience 2021 11:215

    Content type: Viewpoint

    Published on:

  15. Autophagy is a cell self-digestion pathway through lysosome and plays a critical role in maintaining cellular homeostasis and cytoprotection. Characterization of autophagy related genes in cell and animal mode...

    Authors: Zhiqiang Deng, Xiaoting Zhou, Jia-Hong Lu and Zhenyu Yue

    Citation: Cell & Bioscience 2021 11:214

    Content type: Review

    Published on:

  16. Long non-coding RNAs (lncRNAs) have been the focus of ongoing research in a diversity of cellular processes. LncRNAs are abundant in mammalian testis, but their biological function remains poorly known.

    Authors: Zhaohui Chen, Li Ling, Xiaolian Shi, Wu Li, Huicong Zhai, Zhenlong Kang, Bangjin Zheng, Jiaqi Zhu, Suni Ye, Hao Wang, Lingxiu Tong, Juan Ni, Chaoyang Huang, Yang Li and Ke Zheng

    Citation: Cell & Bioscience 2021 11:213

    Content type: Research

    Published on:

  17. Chickens, important food animals and model organisms, are susceptible to many RNA viruses that invade via the nasal cavity. To determine the nasal entry site of the virus and clarify why avians are susceptible...

    Authors: Abid Ullah Shah, Yuchen Li, Wei Ouyang, Zhisheng Wang, Jinjiao Zuo, Song Shi, Qinghua Yu, Jian Lin and Qian Yang

    Citation: Cell & Bioscience 2021 11:212

    Content type: Research

    Published on:

  18. Silent information regulator 6 (SIRT6) is a mammalian homolog of the nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin family. Prior evidences suggested that the anti-inflammatory function ...

    Authors: Ying Zou, Jiaqi Zhang, Jiawei Xu, Lanya Fu, Yizhou Xu, Xianghai Wang, Zhenlin Li, Lixin Zhu, Hao Sun, Hui Zheng and Jiasong Guo

    Citation: Cell & Bioscience 2021 11:210

    Content type: Research

    Published on:

  19. The majority of mammalian genome is composed of non-coding regions, where numerous long non-coding RNAs (lncRNAs) are transcribed. Although lncRNAs have been identified to regulate fundamental biological proce...

    Authors: Mingyang Xin, Qian Guo, Qingchun Lu, Juan Lu, Po-shun Wang, Yun Dong, Tao Li, Ye Chen, Glenn S. Gerhard, Xiao-feng Yang, Michael Autieri and Ling Yang

    Citation: Cell & Bioscience 2021 11:208

    Content type: Research

    Published on:

  20. Vascular aging is associated with remodeling of elastin, one of the main extracellular matrix component of the arterial wall, and production of elastin-derived peptides (EDP). These extracellular matrix degrad...

    Authors: Olivier Bocquet, Dignê Tembely, Damien Rioult, Christine Terryn, Béatrice Romier, Amar Bennasroune, Sébastien Blaise, Hervé Sartelet, Laurent Martiny, Laurent Duca and Pascal Maurice

    Citation: Cell & Bioscience 2021 11:206

    Content type: Research

    Published on:

  21. Mosaic loss of Y chromosome (LOY) is the most common somatic change that occurs in circulating white blood cells of older men. LOY in leukocytes is associated with increased risk for all-cause mortality and a ...

    Authors: Moeen Riaz, Jonas Mattisson, Galina Polekhina, Andrew Bakshi, Jonatan Halvardson, Marcus Danielsson, Adam Ameur, John McNeil, Lars A. Forsberg and Paul Lacaze

    Citation: Cell & Bioscience 2021 11:205

    Content type: Research

    Published on:

  22. Changes in soluble amyloid-beta (Aβ) levels in cerebrospinal fluid (CSF) are detectable at early preclinical stages of Alzheimer’s disease (AD). However, whether Aβ levels can predict downstream AD pathologica...

    Authors: Guilherme Povala, Bruna Bellaver, Marco Antônio De Bastiani, Wagner S. Brum, Pamela C. L. Ferreira, Andrei Bieger, Tharick A. Pascoal, Andrea L. Benedet, Diogo O. Souza, Ricardo M. Araujo, Bruno Zatt, Pedro Rosa-Neto and Eduardo R. Zimmer

    Citation: Cell & Bioscience 2021 11:204

    Content type: Research

    Published on:

  23. IgA nephropathy (IgAN) is the most common primary glomerulonephritis globally. Increasing evidence suggests the importance of host immunity in the development of IgAN, but its dynamics during the early stage o...

    Authors: Honghui Zeng, Le Wang, Jiajia Li, Siweier Luo, Qianqian Han, Fang Su, Jing Wei, Xiaona Wei, Jianping Wu, Bin Li, Jingang Huang, Patrick Tang, Chunwei Cao, Yiming Zhou and Qiongqiong Yang

    Citation: Cell & Bioscience 2021 11:203

    Content type: Database

    Published on:

  24. The ongoing COVID-19 pandemic has resulted in 185 million recorded cases and over 4 million deaths worldwide. Several COVID-19 vaccines have been approved for emergency use in humans and are being used in many...

    Authors: Huibi Cao, Juntao Mai, Zhichang Zhou, Zhijie Li, Rongqi Duan, Jacqueline Watt, Ziyan Chen, Ranmal Avinash Bandara, Ming Li, Sang Kyun Ahn, Betty Poon, Natasha Christie-Holmes, Scott D. Gray-Owen, Arinjay Banerjee, Karen Mossman, Rob Kozak…

    Citation: Cell & Bioscience 2021 11:202

    Content type: Research

    Published on:

  25. Fatty acids (FA) derived from adipose tissue and liver serve as the main fuel in thermogenesis of brown adipose tissue (BAT). Catalase, a peroxisomal enzyme, plays an important role in maintaining intracellula...

    Authors: Raghbendra Kumar Dutta, Joon No Lee, Yunash Maharjan, Channy Park, Seong-Kyu Choe, Ye-Shih Ho and Raekil Park

    Citation: Cell & Bioscience 2021 11:201

    Content type: Research

    Published on:

  26. Doxorubicin (Dox) is a widely used anthracycline drug to treat cancer, yet numerous adverse effects influencing different organs may offset the treatment outcome, which in turn affects the patient’s quality of...

    Authors: Hsiu-Chung Ou, Pei-Ming Chu, Yu-Ting Huang, Hui-Ching Cheng, Wan-Ching Chou, Hsin-Lun Yang, Hsiu-I. Chen and Kun-Ling Tsai

    Citation: Cell & Bioscience 2021 11:200

    Content type: Research

    Published on:

  27. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible and has caused a pandemic named coronavirus disease 2019 (COVID-19), which has quickly spread worldwide. Although several th...

    Authors: Gangan Yan, Dongsheng Li, Yuan Lin, Zhenghao Fu, Haiyan Qi, Xiaoping Liu, Jing Zhang, Shuyi Si and Yunyu Chen

    Citation: Cell & Bioscience 2021 11:199

    Content type: Methodology

    Published on:

  28. There is currently a critical need to determine the efficacy of SARS-CoV-2 vaccination for immunocompromised patients. In this study, we determined the neutralizing antibody response in 160 cancer patients dia...

    Authors: Cong Zeng, John P. Evans, Sarah Reisinger, Jennifer Woyach, Christina Liscynesky, Zeinab El Boghdadly, Mark P. Rubinstein, Karthik Chakravarthy, Linda Saif, Eugene M. Oltz, Richard J. Gumina, Peter G. Shields, Zihai Li and Shan-Lu Liu

    Citation: Cell & Bioscience 2021 11:197

    Content type: Letter to the Editor

    Published on:

  29. Dementia with Lewy bodies (DLB) is epitomized by the pathognomonic manifestation of α-synuclein-laden Lewy bodies within selectively vulnerable neurons in the brain. By virtue of prion-like inheritance, the α-...

    Authors: Christopher Simon, Tomoko Soga, Hirotaka James Okano and Ishwar Parhar

    Citation: Cell & Bioscience 2021 11:196

    Content type: Review

    Published on:

  30. NME6 is a member of the nucleoside diphosphate kinase (NDPK/NME/Nm23) family which has key roles in nucleotide homeostasis, signal transduction, membrane remodeling and metastasis suppression. The well-studied...

    Authors: Bastien Proust, Martina Radić, Nikolina Škrobot Vidaček, Cécile Cottet, Stéphane Attia, Frédéric Lamarche, Lucija Ačkar, Vlatka Godinić Mikulčić, Malgorzata Tokarska-Schlattner, Helena Ćetković, Uwe Schlattner and Maja Herak Bosnar

    Citation: Cell & Bioscience 2021 11:195

    Content type: Research

    Published on:

  31. Methamphetamine (METH), a potent addictive psychostimulant, is highly prevalent in HIV-infected individuals. Clinically, METH use is implicated in alteration of immune system and increase of HIV spread/replica...

    Authors: Yu Liu, Feng-Zhen Meng, Xu Wang, Peng Wang, Jin-Biao Liu, Wen-Hui Hu, Won-Bin Young and Wen-Zhe Ho

    Citation: Cell & Bioscience 2021 11:194

    Content type: Research

    Published on:

  32. As the predominant host defense against pathogens, neutrophil extracellular traps (NETs) have attracted increasing attention due to their vital roles in infectious inflammation in the past few years. Interesti...

    Authors: Hui Wang, Yiyin Zhang, Qianling Wang, Xiaoli Wei, Hua Wang and Kangsheng Gu

    Citation: Cell & Bioscience 2021 11:193

    Content type: Review

    Published on:

  33. Aging and neurodegenerative diseases are typical metabolic-related processes. As a metabolism-related long non-coding RNA, EPB41L4A-AS has been reported to be potentially involved in the development of brain a...

    Authors: Tingpeng Yang, Yanzhi Wang, Weijie Liao, Shikuan Zhang, Songmao Wang, Naihan Xu, Weidong Xie, Cheng Luo, Yangyang Wang, Ziqiang Wang and Yaou Zhang

    Citation: Cell & Bioscience 2021 11:192

    Content type: Research

    Published on:

  34. Gonadotropin-releasing hormone receptor (GnRHR) transmits its signal via two major Gα-proteins, primarily Gαq and Gαi. However, the precise mechanism underlying the functions of Gαs signal in prostate cancer c...

    Authors: Ji Won Kim, Miso Park, Suntae Kim, Sung Chul Lim, Hyung Shik Kim and Keon Wook Kang

    Citation: Cell & Bioscience 2021 11:191

    Content type: Research

    Published on:

  35. Patients with Parkinson’s disease (PD) exhibit systemic deficits, including arthritis and osteoporosis-like symptoms. However, the questions, how the deficits in periphery organs or tissues occur in PD patient...

    Authors: Lei Xiong, Jin-Xiu Pan, Hao-han Guo, Lin Mei and Wen-Cheng Xiong

    Citation: Cell & Bioscience 2021 11:190

    Content type: Review

    Published on:

  36. Nonalcoholic fatty liver disease (NAFLD) is a disorder that extends from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH), which is effectively alleviated by lifestyle intervention. Nevertheless...

    Authors: Na Wu, Fan Yuan, Siran Yue, Fengyan Jiang, Decheng Ren, Liangjie Liu, Yan Bi, Zhenming Guo, Lei Ji, Ke Han, Xiao Yang, Mofan Feng, Kai Su, Fengping Yang, Xi Wu, Qing Lu…

    Citation: Cell & Bioscience 2021 11:189

    Content type: Research

    Published on:

  37. The proline rich mitotic checkpoint control factor (PRCC) is involved in the splicing process of pre-mRNA. This study aims to elucidate PRCC molecular function, regulatory mechanism and diagnostic value in hep...

    Authors: Chunying Liu, Xuejing Lin, Bin Sun, Ziming Mao, Lei Chen, Haihua Qian and Changqing Su

    Citation: Cell & Bioscience 2021 11:185

    Content type: Research

    Published on:

  38. Authors: Beibei Wu, Wenlong Zhu, Yue Wang, Qi Wang, Lin Zhou, Zhengwei Liu, Lijun Bi, Mathema Barun, Barry N. Kreiswirth, Liang Chen, Songhua Chen, Xiaomeng Wang and Weibing Wang

    Citation: Cell & Bioscience 2021 11:184

    Content type: Correction

    Published on:

    The original article was published in Cell & Bioscience 2021 11:162

  39. Articular cartilage is a complex tissue with poor healing capacities. Current approaches for cartilage repair based on mesenchymal stromal cells (MSCs) are often disappointing because of the lack of relevant d...

    Authors: Marie Maumus, Guillaume Fonteneau, Maxime Ruiz, Said Assou, Hassan Boukhaddaoui, Philippe Pastoureau, Frédéric De Ceuninck, Christian Jorgensen and Danièle Noel

    Citation: Cell & Bioscience 2021 11:183

    Content type: Research

    Published on:

  40. Trophoblast dysfunction during pregnancy is fundamentally involved in preeclampsia. Several studies have revealed that human chorionic villous mesenchymal stem cells (CV-MSCs) could regulate trophoblasts funct...

    Authors: Yijing Chu, Chengzhan Zhu, Chongyu Yue, Wei Peng, Weiping Chen, Guifang He, Changchang Liu, Yang Lv, Guoqiang Gao, Ke Yao, Rendong Han, Xiaoyu Hu, Yan Zhang and Yuanhua Ye

    Citation: Cell & Bioscience 2021 11:182

    Content type: Research

    Published on:

  41. During the last decades, numerous basic and clinical studies have been conducted to assess the delivery efficiency of therapeutic agents into the brain and spinal cord parenchyma using several administration r...

    Authors: Gozal Bahlakeh, Reza Rahbarghazi, Daruosh Mohammadnejad, Ali Abedelahi and Mohammad Karimipour

    Citation: Cell & Bioscience 2021 11:181

    Content type: Review

    Published on: