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  1. Content type: Research

    Diabetes mellitus is associated with an increased risk in diabetic cardiomyopathy (DCM) that is distinctly not attributed to co-morbidities with other vasculature diseases. To date, while dysregulation of calc...

    Authors: Khampaseuth Thapa, Kai Connie Wu, Aishwarya Sarma, Eric M. Grund, Angela Szeto, Armando J. Mendez, Stephane Gesta, Vivek K. Vishnudas, Niven R. Narain and Rangaprasad Sarangarajan

    Citation: Cell & Bioscience 2018 8:45

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  2. Content type: Research

    Notch signaling is mainly regulated by Notch1 during development of chicken germ stem cells; however, the molecular mechanisms that contribute to generation of these germ stem cells have not been thoroughly in...

    Authors: Qisheng Zuo, Chen Zhang, Kai Jin, Jin Jing, Changhua Sun, Mahmoud F. Ahmed, Jiuzhou Song, Yani Zhang, Guohong Chen and Bichun Li

    Citation: Cell & Bioscience 2018 8:40

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  3. Content type: Research

    This study investigated the role of HSP70 in modulating intestinal γδ T cells’ Th17 response in Trichinella spiralis-induced PI-IBS mice model.

    Authors: Zhoutao He, Xiaoning Sun, Zhichao Ma, Jiao Fu, Baili Huang, Fujin Liu, Yi Chen, Taozhi Deng, Xiangyang Han, Deming Sun and Cheng Lan

    Citation: Cell & Bioscience 2018 8:38

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  4. Content type: Research

    As an important danger signal, the presence of DNA in cytoplasm triggers potent immune responses. Cyclic GMP-AMP synthase (cGAS) is a recently characterized key sensor for cytoplasmic DNA. The engagement of cG...

    Authors: Zhao-Shan Liu, Zi-Yu Zhang, Hong Cai, Ming Zhao, Jie Mao, Jiang Dai, Tian Xia, Xue-Min Zhang and Tao Li

    Citation: Cell & Bioscience 2018 8:35

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  5. Content type: Letter to the Editor

    Two studies have recently focused on adult heart regeneration in Xenopus. While we reported on cardiac myogenic regeneration in Xenopus tropicalis after injury, Marshall and colleagues found no regeneration in an...

    Authors: Souqi Liao, Wenyan Dong, Hui Zhao, Ruijin Huang, Xufeng Qi and Dongqing Cai

    Citation: Cell & Bioscience 2018 8:32

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  6. Content type: Letter to the Editor

    We recently used an endoscopy-based resection method to explore the consequences of cardiac injury in adult Xenopus laevis, obtaining the result that the adult Xenopus heart is unable to regenerate. At 11 months ...

    Authors: Lindsey Marshall, Fabrice Girardot, Barbara A. Demeneix and Laurent Coen

    Citation: Cell & Bioscience 2018 8:31

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  7. Content type: Viewpoint

    Antibodies to human CTLA-4 have been shown to induce long-lasting protection against melanoma. It is assumed that these antibodies cause tumor rejection by blocking negative signaling from the B7-CTLA-4 intera...

    Authors: Fei Tang, Xuexiang Du, Mingyue Liu, Pan Zheng and Yang Liu

    Citation: Cell & Bioscience 2018 8:30

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  8. Content type: Research

    microRNAs (miRNAs) are one kind of small non-coding RNAs widely distributed in insects. Many studies have shown that miRNAs play critical roles in development, differentiation, apoptosis, and innate immunity. ...

    Authors: Xinyu Feng, Jiatong Wu, Shuisen Zhou, Jingwen Wang and Wei Hu

    Citation: Cell & Bioscience 2018 8:29

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  9. Content type: Letter to the Editor

    Organ preservation solutions are designed to minimize organ damage during transplantation. A novel preservation solution, WMO-II, was developed to have a low viscosity and to improve microvasculature perfusion...

    Authors: Sheng Wang, Kristyn Gumpper, Tao Tan, Xianzhang Luo, Hui Guo, Changsheng Ming, Hanying Jiang, Jiangguo Fang, Guang Du, Hua Zhu, Jianjie Ma, Zhishui Chen and Nianqiao Gong

    Citation: Cell & Bioscience 2018 8:28

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  10. Content type: Research

    Innate immunity activator (INAVA) has been shown to be elevated in lung adenocarcinoma. However, its expression pattern and function in papillary thyroid cancer (PTC) are unknown. This study aimed to identify ...

    Authors: Hongyu Guan, Yan Guo, Liehua Liu, Runyi Ye, Weiwei Liang, Hai Li, Haipeng Xiao and Yanbing Li

    Citation: Cell & Bioscience 2018 8:26

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  11. Content type: Research

    Radiation injury combined wound (CI) enhances acute radiation syndrome and subsequently mortality as compared to radiation injury alone (RI). We previously reported that ghrelin (a 28-amino-acid-peptide secret...

    Authors: Juliann G. Kiang, Marsha N. Anderson and Joan T. Smith

    Citation: Cell & Bioscience 2018 8:27

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  12. Content type: Review

    Although the study of calcium (Ca2+) is classically associated with excitable cells such as myocytes or neurons, the ubiquity of this essential element in all cellular processes has led to interest in other cell ...

    Authors: MengMeng Xu, Andreas Seas, Musa Kiyani, Keven S. Y. Ji and Hannah N. Bell

    Citation: Cell & Bioscience 2018 8:25

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  13. Content type: Review

    Macrophages are traditionally viewed as a key component of the immunity defense system. Recent studies have identified resident macrophages in multiple organs including the heart, in which the cells perform th...

    Authors: Xin Zhou, Zhongguang Li, Zefan Wang, Eda Chen, Juan Wang, Frederic Chen, Odell Jones, Tao Tan, Shawn Chen, Hiroshi Takeshima, Joseph Bryant, Jianjie Ma and Xuehong Xu

    Citation: Cell & Bioscience 2018 8:24

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  14. Content type: Research

    The acquisition of drug resistance has been considered as a main obstacle for cancer chemotherapy. Tumor protein 53 target gene 1 (TP53TG1), a p53-induced lncRNA, plays a vital role in the progression of human...

    Authors: Huijuan Xiao, Yihe Liu, Pan Liang, Bo Wang, Hongna Tan, Yonggao Zhang, Xianzheng Gao and Jianbo Gao

    Citation: Cell & Bioscience 2018 8:23

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  15. Content type: Research

    Biomaterial modifications—chemical and topographical—are of particular importance for the integration of materials in biosystems. Cells are known to sense these biomaterial characteristics, but it has remained...

    Authors: Susanne Staehlke, Henrike Rebl, Birgit Finke, Petra Mueller, Martina Gruening and J. Barbara Nebe

    Citation: Cell & Bioscience 2018 8:22

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  16. Content type: Research

    Paraquat (PQ) presents with high toxicity for humans and animals, and the lungs become the main target organ by the poisoning of PQ leading to acute lung injury. Endothelial progenitor cells (EPCs) were proved...

    Authors: Yan Jin, Wei Liu, Xiaowei Liu, Tao Ma, Chen Yang, Quan Cai and Zhi Liu

    Citation: Cell & Bioscience 2018 8:21

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  17. Content type: Correction

    In the publication of this article [1], there is an error in Table 3. The position of the black arrow and the terms CBP, Cdk1/2 and STAT3 of Table 3 were placed incorrectly in the online version while these we...

    Authors: Kuo-Sheng Hsu and Hung-Ying Kao

    Citation: Cell & Bioscience 2018 8:18

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    The original article was published in Cell & Bioscience 2018 8:5

  18. Content type: Review

    Prostate cancer (PrCa) progression and mortality are associated with calcium metabolism, parathyroid hormone level, and vitamin D level. However, the lack of comprehensive understanding on the molecular ration...

    Authors: Liyang Wang, MengMeng Xu, Zhongguang Li, Mengting Shi, Xin Zhou, Xinnong Jiang, Joseph Bryant, Steven Balk, Jianjie Ma, William Isaacs and Xuehong Xu

    Citation: Cell & Bioscience 2018 8:16

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  19. Content type: Research

    Apoptosis of lung epithelial cell is implicated in the pathogenesis of acute lung injury (ALI). To study the protective effect and mechanism of cancer susceptibility candidate 2 (CASC2) on reducing lung epithe...

    Authors: Hongbin Li, Huijuan Shi, Min Gao, Ning Ma and Rongqing Sun

    Citation: Cell & Bioscience 2018 8:15

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  20. Content type: Research

    Histamine releasing factor (HRF) is a unique cytokine known to regulate a variety of immune cells in late allergic reactions. In the previous study, we revealed that the biologically active form of HRF is the ...

    Authors: Heewon Lee and Kyunglim Lee

    Citation: Cell & Bioscience 2018 8:13

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  21. Content type: Research

    Chronic hepatitis B (CHB) remains a global health dilemma with high morbidity and mortality. Human males absent on the first (hMOF) (a histone acetyltransferase) is responsible for DNA damage repair, tumorigen...

    Authors: Liwen Chen, Chuanwu Zhu, Fengdi Li, Yun Wang, Rebecca Bao, Zhujun Cao, Xiaogang Xiang, Lei Yan, Lanyi Lin, Gangde Zhao, Qing Xie, Shisan Bao and Hui Wang

    Citation: Cell & Bioscience 2018 8:14

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  22. Content type: Research

    Precise genome editing is essential for both basic and translational research. The recently developed CRISPR/Cas9 system can specifically cleave a designated site of target gene to create a DNA double-strand b...

    Authors: Zheng Hu, Zhaoying Shi, Xiaogang Guo, Baishan Jiang, Guo Wang, Dixian Luo, Yonglong Chen and Yuan-Shan Zhu

    Citation: Cell & Bioscience 2018 8:12

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  23. Content type: Research

    Rheumatoid arthritis (RA) is an auto-immune disease characterized by chronic inflammation of multiple joints. Hypoxia is a constant feature of synovial microenvironment in RA. Fibroblast-like synoviocytes (FLS...

    Authors: Ru Yang, Yanhua Yao and Panjun Wang

    Citation: Cell & Bioscience 2018 8:11

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  24. Content type: Review

    Sepsis is a common cause of death in intensive care units worldwide. Due to the high complexity of this immunological syndrome development of novel therapeutic strategies is urgent. Promising drug targets or b...

    Authors: Katharina Rump and Michael Adamzik

    Citation: Cell & Bioscience 2018 8:10

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  25. Content type: Research

    ATP-binding cassette transporter super-family including ABCC1 and MDR-1 were involved in multi-drug resistance (MDR) of renal cell carcinoma (RCC) patients. Several miRNAs were confirmed to promote the MDR and...

    Authors: Songchao Li, Jinjian Yang, Jun Wang, Wansheng Gao, Yafei Ding, Yinghui Ding and Zhankui Jia

    Citation: Cell & Bioscience 2018 8:9

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  26. Content type: Review

    Long noncoding RNAs (lncRNAs) are a class of non-protein-coding transcripts with the length longer than 200 nucleotides. Growing evidence suggests that lncRNAs, which were initially thought to be merely transc...

    Authors: Yuyu Li, Jiawei Zhang, Jie Pan, Xu Feng, Peipei Duan, Xing Yin, Yang Xu, Xin Wang and Shujuan Zou

    Citation: Cell & Bioscience 2018 8:8

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  27. Content type: Research

    MAPT-AS1, a long non-coding RNA, has not been reported in any previous research about its function in cancers. In this study, we investigated the role of MAPT-AS1 in the progression and paclitaxel resistance i...

    Authors: Yiyuan Pan, Yiqi Pan, Yue Cheng, Fan Yang, Zhihan Yao and Ouchen Wang

    Citation: Cell & Bioscience 2018 8:7

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  28. Content type: Review

    There have been enough cell death modes delineated in the biomedical literature to befuddle all cell death researchers. Mulling over cell death from the viewpoints of the host tissue or organ and of the host a...

    Authors: Xingde Liu, Wenxiu Yang, Zhizhong Guan, Wenfeng Yu, Bin Fan, Ningzhi Xu and D. Joshua Liao

    Citation: Cell & Bioscience 2018 8:6

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  29. Content type: Review

    Promyelocytic leukemia protein (PML) was originally identified as a fusion partner of retinoic acid receptor alpha in acute promyelocytic leukemia patients with the (15;17) chromosomal translocation, giving ri...

    Authors: Kuo-Sheng Hsu and Hung-Ying Kao

    Citation: Cell & Bioscience 2018 8:5

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    The Correction to this article has been published in Cell & Bioscience 2018 8:18

  30. Content type: Research

    We investigated the genomic DNA methylation profile of prostate cancer in transgenic adenocarcinoma of the mouse prostate (TRAMP) cancer model and to analyze the crosstalk among targeted genes and the related ...

    Authors: Wenji Li, Ying Huang, Davit Sargsyan, Tin Oo Khor, Yue Guo, Limin Shu, Anne Yuqing Yang, Chengyue Zhang, Ximena Paredes-Gonzalez, Michael Verzi, Ronald P. Hart and Ah-Ng Kong

    Citation: Cell & Bioscience 2018 8:3

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  31. Content type: Research

    Extracellular vesicles (EVs) play important roles in intercellular communication through the delivery of their cargoes, which include proteins, lipids, and RNAs. Increasingly, multiple studies have reported th...

    Authors: Chuang Li, Fang Qin, Fen Hu, Hui Xu, Guihong Sun, Guang Han, Tao Wang and Mingxiong Guo

    Citation: Cell & Bioscience 2018 8:2

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  32. Content type: Research

    The metastasis of colorectal cancer frequently tends to liver, which is one of the three leading causes of cancer-related deaths worldwide. Growing evidence showed that aspirin could effectively inhibit liver ...

    Authors: Jun Ying, Hai-yang Zhou, Peng Liu, Qing You, Fei Kuang, Yi-nan Shen and Zhi-qian Hu

    Citation: Cell & Bioscience 2018 8:1

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  33. Content type: Research

    The aim of this study is to determine the effect of hypoxia on axitinib and sorafenib-treated renal cell carcinoma (RCC) cells. Hypoxia is a crucial factor influencing transcription process via protein modulat...

    Authors: Zofia F. Bielecka, Agata Malinowska, Klaudia K. Brodaczewska, Aleksandra Klemba, Claudine Kieda, Paweł Krasowski, Elżbieta Grzesiuk, Jan Piwowarski, Anna M. Czarnecka and Cezary Szczylik

    Citation: Cell & Bioscience 2017 7:71

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  34. Content type: Research

    Myocardium regeneration in adult mammals is very limited, but has enormous therapeutic potentials. However, we are far from complete understanding the cellular and molecular mechanisms by which heart tissue ca...

    Authors: Souqi Liao, Wenyan Dong, Luocheng Lv, Hongyan Guo, Jifeng Yang, Hui Zhao, Ruijin Huang, Ziqiang Yuan, Yilin Chen, Shanshan Feng, Xin Zheng, Junqi Huang, Weihuan Huang, Xufeng Qi and Dongqing Cai

    Citation: Cell & Bioscience 2017 7:70

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  35. Content type: Research

    A gasotransmitter hydrogen sulfide (H2S) plays an important physiological and pathological role in cardiovascular system. Ischemic post-conditioning (PC) provides cardioprotection in the young hearts but not in t...

    Authors: Weiming Sun, Jinxia Yang, Yuanzhou Zhang, Yuxin Xi, Xin Wen, Di Yuan, Yuehong Wang, Can Wei, Rui Wang, Lingyun Wu, Hongzhu Li and Changqing Xu

    Citation: Cell & Bioscience 2017 7:67

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  36. Content type: Research

    Neural stem cells (NSCs) are able to differentiate into neurons and astroglia. miRNAs have been demonstrated to be involved in NSC self-renewal, proliferation and differentiation. However, the exact role of mi...

    Authors: Shujie Jiao, Yaling Liu, Yaobing Yao and Junfang Teng

    Citation: Cell & Bioscience 2017 7:68

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