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  1. PRAME constitutes one of the largest multi-copy gene families in Eutherians, encoding cancer-testis antigens (CTAs) with leucine-rich repeats (LRR) domains, highly expressed in cancer cells and gametogenic ger...

    Authors: Mingyao Yang, Francisco Diaz, Ana Rita T. Krause, Yuguo Lei and Wan-Sheng Liu
    Citation: Cell & Bioscience 2024 14:28
  2. Sodium-Glucose cotransporter 1 and 2 (SGLT1/2) belong to the family of glucose transporters, encoded by SLC5A1 and SLC5A2, respectively. SGLT2 is almost exclusively expressed in the renal proximal convoluted tubu...

    Authors: Yifei Sun, Yihan Zhang, Jifeng Zhang, Y. Eugene Chen, Jian-Ping Jin, Kezhong Zhang, Hongmei Mou, Xiubin Liang and Jie Xu
    Citation: Cell & Bioscience 2024 14:27
  3. Archetypical cross-β spines sharpen the boundary between functional and pathological proteins including β-amyloid, tau, α-synuclein and transthyretin are linked to many debilitating human neurodegenerative and...

    Authors: Karthika Suresh, Eshan Dahal and Aldo Badano
    Citation: Cell & Bioscience 2024 14:26
  4. Patients with cirrhosis have intestinal barrier dysfunction but the role of the individual cell types in human small intestine is unclear. We performed single-nuclear RNA sequencing (snRNAseq) in the pinch bio...

    Authors: Xixian Jiang, Ying Xu, Andrew Fagan, Bhaumik Patel, Huiping Zhou and Jasmohan S. Bajaj
    Citation: Cell & Bioscience 2024 14:25
  5. Vaccination is a valid strategy to prevent and control newly emerging and reemerging infectious diseases in humans and animals. However, synthetic and recombinant antigens are poor immunogenic to stimulate eff...

    Authors: Guangyu Wang, Yongkang Wang and Fang Ma
    Citation: Cell & Bioscience 2024 14:24
  6. Viral infection elicits the type I interferon (IFN-I) response in host cells and subsequently inhibits viral infection through inducing hundreds of IFN-stimulated genes (ISGs) that counteract many steps in the...

    Authors: Qiaomei Cai, Nina Sun, Yurui Zhang, Jingfeng Wang, Chaohu Pan, Yu Chen, Lili Li, Xiaorong Li, Wancheng Liu, Saba R. Aliyari, Heng Yang and Genhong Cheng
    Citation: Cell & Bioscience 2024 14:23
  7. Protein post-translational modifications (PPTMs) refer to a series of chemical modifications that occur after the synthesis of protein. Proteins undergo different modifications such as phosphorylation, acetyla...

    Authors: Wei Li, Hong-Lian Li, Jian-Zhi Wang, Rong Liu and Xiaochuan Wang
    Citation: Cell & Bioscience 2024 14:22
  8. Neovascular eye disease is characterized by pathological neovascularization, with clinical manifestations such as intraocular exudation, bleeding, and scar formation, ultimately leading to blindness in million...

    Authors: Peiyu Liu, Dandan Sun, Shuchang Zhang, Shimei Chen, Xiaoqian Wang, Huiming Li and Fang Wei
    Citation: Cell & Bioscience 2024 14:21
  9. Within the last decade, poly(ADP-ribose) polymerase inhibitors (PARPi) have emerged in the clinic as an effective treatment for numerous malignancies. Preclinical data have demonstrated powerful combination ef...

    Authors: Aaron Sorrin, Anika Dasgupta, Kathryn McNaughton, Carla Arnau Del Valle, Keri Zhou, Cindy Liu, Dana M. Roque and Huang Chiao Huang
    Citation: Cell & Bioscience 2024 14:20
  10. The tumour microenvironment (TME) consists of tumour-supportive immune cells, endothelial cells, and fibroblasts. PhenoCycler, a high-plex single cell spatial biology imaging platform, is used to characterize ...

    Authors: Madelyn J. Abraham, Christophe Goncalves, Paige McCallum, Vrinda Gupta, Samuel E. J. Preston, Fan Huang, Hsiang Chou, Natascha Gagnon, Nathalie A. Johnson, Wilson H. Miller, Koren K. Mann and Sonia V. del Rincon
    Citation: Cell & Bioscience 2024 14:19
  11. The development of alcohol-associated liver disease (ALD) is influenced by the amount and duration of alcohol consumption. The resulting liver damage can range from reversible stages, such as steatosis, steato...

    Authors: Ying-Wei Lan, Wan-Ru Chen, Gary Ro-Lin Chang, Ying-Cheng Chen, Kowit-Yu Chong, Kai-Cheng Chuang, Yung-Tsung Kao, Ming-Shan Chen and Chuan-Mu Chen
    Citation: Cell & Bioscience 2024 14:18
  12. Sexual dimorphism represents a key concept in the comprehension of molecular processes guiding several sex-specific physiological and pathological mechanisms. It has been reported that genes involved in many d...

    Authors: Ludovica Celli, Patrizia Gasparini, Ginevra Biino, Laura Zannini and Miriana Cardano
    Citation: Cell & Bioscience 2024 14:15
  13. Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by progressive biliary inflammation and bile duct injury. Berberine (BBR) is a bioactive isoquinoline alkaloid found in various her...

    Authors: Yanyan Wang, Derrick Zhao, Lianyong Su, Yun-Ling Tai, Grayson W. Way, Jing Zeng, Qianhua Yan, Ying Xu, Xuan Wang, Emily C. Gurley, Xi-Qiao Zhou, Jinze Liu, Jinpeng Liu, Weidong Chen, Phillip B. Hylemon and Huiping Zhou
    Citation: Cell & Bioscience 2024 14:14
  14. Rasal1 is a Ras GTPase-activating protein which contains C2 domains necessary for dynamic membrane association following intracellular calcium elevation. Membrane-bound Rasal1 inactivates Ras signaling through...

    Authors: M. H. S. Deurloo, S. Eide, E. Turlova, Q. Li, S. Spijker, H.-S. Sun, A. J. A. Groffen and Z.-P. Feng
    Citation: Cell & Bioscience 2024 14:13
  15. The enrichment of peri-cancerous adipose tissue is a distinctive feature of colorectal cancer (CRC), accelerating disease progression and worsening prognosis. The communication between tumor cells and adjacent...

    Authors: Qinhao Wang, Yuanyuan Su, Ruiqi Sun, Xin Xiong, Kai Guo, Mengying Wei, Guodong Yang, Yi Ru, Zhengxiang Zhang, Jing Li, Jing Zhang, Qing Qiao and Xia Li
    Citation: Cell & Bioscience 2024 14:12
  16. METTL3 plays a significant role as a catalytic enzyme in mediating N6-methyladenosine (m6A) modification, and its importance in tumour progression has been extensively studied in recent years. However, the precis...

    Authors: Wangyang Meng, Han Xiao, Rong Zhao, Jiaping Chen, Yangwei Wang, Peiyuan Mei, Hecheng Li and Yongde Liao
    Citation: Cell & Bioscience 2024 14:10
  17. Thymidine analogs have long been recognized for their ability to randomly incorporate into DNA. However, the precise mechanisms through which thymidine analogs facilitate cell fate transition remains unclear.

    Authors: Chuang Li, Xiaoduo Xu, Shuyan Chen, Anchun Xu, Tongxing Guan, Haokaifeng Wu, Duanqing Pei and Jing Liu
    Citation: Cell & Bioscience 2024 14:9
  18. Alzheimer’s disease (AD) diagnosis relies on clinical symptoms complemented with biological biomarkers, the Amyloid Tau Neurodegeneration (ATN) framework. Small non-coding RNA (sncRNA) in the blood have emerge...

    Authors: Laia Gutierrez-Tordera, Christopher Papandreou, Nil Novau-Ferré, Pablo García-González, Melina Rojas, Marta Marquié, Luis A. Chapado, Christos Papagiannopoulos, Noèlia Fernàndez-Castillo, Sergi Valero, Jaume Folch, Miren Ettcheto, Antoni Camins, Mercè Boada, Agustín Ruiz and Mònica Bulló
    Citation: Cell & Bioscience 2024 14:8
  19. Metabolic dysfunction is one of the main symptoms of Werner syndrome (WS); however, the underlying mechanisms remain unclear. Here, we report that loss of WRN accelerates adipogenesis at an early stage both in vi...

    Authors: Yuyao Tian, Sofie Lautrup, Patrick Wai Nok Law, Ngoc-Duy Dinh, Evandro Fei Fang and Wai-Yee Chan
    Citation: Cell & Bioscience 2024 14:7
  20. Hair follicle stem cells (HFSCs) typically remain quiescent and are activated only during the transition from telogen to anagen to ensure that the hair follicle enters a new cycle. The metabolic behavior of st...

    Authors: Pingping Sun, Zhan Wang, Sixiao Li, Jiajing Yin, Yuyang Gan, Shizhao Liu, Zhen Lin, Hailin Wang, Zhexiang Fan, Qian Qu, Zhiqi Hu, Kaitao Li and Yong Miao
    Citation: Cell & Bioscience 2024 14:6
  21. Glaucoma, a progressive neurodegenerative disease, is a leading cause of irreversible vision loss worldwide. This study aims to elucidate the critical role of Müller glia (MG) in the context of retinal ganglio...

    Authors: Xandra Pereiro, Noelia Ruzafa, Mikel Azkargorta, Félix Elortza, Arantxa Acera, António Francisco Ambrósio, Ana Raquel Santiago and Elena Vecino
    Citation: Cell & Bioscience 2024 14:5
  22. The absence of expression of the Y-chromosome linked testis-determining gene SRY in early supporting gonadal cells (ESGC) leads bipotential gonads into ovarian development. However, genetic variants in NR2F2, enc...

    Authors: Lucas G. A. Ferreira, Marina M. L. Kizys, Gabriel A. C. Gama, Svenja Pachernegg, Gorjana Robevska, Andrew H. Sinclair, Katie L. Ayers and Magnus R. Dias-da-Silva
    Citation: Cell & Bioscience 2024 14:3
  23. Attention provides the foundation for cognitions, which was shown to be affected by microwave (MW) radiation. With the ubiquitous of microwaves, public concerns regarding the impact of MW radiation on attentio...

    Authors: Shaofei Jiang, Yingping Ma, Yuan Shi, Yong Zou, Zhenqi Yang, Weijia Zhi, Zhe Zhao, Wei Shen, Liping Chen, Yan Wu, Lifeng Wang, Xiangjun Hu and Haitao Wu
    Citation: Cell & Bioscience 2024 14:2
  24. Previously, we found that FK506 binding protein 51 (Fkbp51) knockout (KO) mice resist high fat diet-induced fatty liver and alcohol-induced liver injury. The aim of this research is to identify the mechanism of F...

    Authors: Bin Qiu, Zhaohui Zhong, Longyu Dou, Yuxue Xu, Yi Zou, Korri Weldon, Jun Wang, Lingling Zhang, Ming Liu, Kent E. Williams, John Paul Spence, Richard L. Bell, Zhao Lai, Weidong Yong and Tiebing Liang
    Citation: Cell & Bioscience 2024 14:1
  25. mTORC2 is a critical regulator of cytoskeleton organization, cell proliferation, and cancer cell survival. Activated mTORC2 induces maximal activation of Akt by phosphorylation of Ser-473, but regulation of Ak...

    Authors: Mario Palma, Elizabeth Riffo, Alejandro Farias, Viviana Coliboro-Dannich, Luis Espinoza-Francine, Emilia Escalona, Roberto Amigo, José L. Gutiérrez, Roxana Pincheira and Ariel F. Castro
    Citation: Cell & Bioscience 2023 13:232
  26. Nephrotoxicity is a significant concern during the development of new drugs or when assessing the safety of chemicals in consumer products. Traditional methods for testing nephrotoxicity involve animal models ...

    Authors: Pengfei Yu, Hainan Zhu, Carol Christine Bosholm, Daniella Beiner, Zhongping Duan, Avinash K. Shetty, Steve S. Mou, Philip Adam Kramer, Luis F. Barroso, Hongbing Liu, Kun Cheng, Michael Ihnat, Matthew A. Gorris, Joseph A. Aloi, Jobira A. Woldemichael, Anthony Bleyer…
    Citation: Cell & Bioscience 2023 13:231
  27. Type I interferon (IFN-I) plays crucial roles in the regulation of inflammation and it is associated with various inflammatory diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), ...

    Authors: Ling Ji, Tianle Li, Huimin Chen, Yanqi Yang, Eryi Lu, Jieying Liu, Wei Qiao and Hui Chen
    Citation: Cell & Bioscience 2023 13:230
  28. Congenital heart defects (CHDs) are the most common birth defects. Assessment of the incidence, distribution, disease spectrum, and genetic deficits of fetal CHDs in China is urgently needed.

    Authors: Xinlin Chen, Sheng Zhao, Xiaoyan Dong, Juntao Liu, Yulin Guo, Weina Ju, Peiwen Chen, Yanduo Gao, Qian Feng, Xia Zhu, Hui Huang, Xiaojun Lu, Xiaohong Yang, Fan Yang, Chen Cheng, Xishun Luo…
    Citation: Cell & Bioscience 2023 13:229
  29. Cancer is an aging-related disease, while aging plays an important role in the development process of tumor, thus the two are inextricably associated. Telomere attrition is one of the recognized hallmark event...

    Authors: Siyu Yan, Song Lin, Hongxin Qiu, Xining Wang, Yijun He, Chuanle Wang and Yan Huang
    Citation: Cell & Bioscience 2023 13:228
  30. Various craniofacial syndromes cause skeletal malformations and are accompanied by neurological abnormalities at different levels, leading to tremendous biomedical, financial, social, and psychological burdens...

    Authors: Chenshuang Li, Zhong Zheng, Pin Ha, Wenlu Jiang, Chia Soo and Kang Ting
    Citation: Cell & Bioscience 2023 13:227
  31. In multicellular organisms, regulatory cell death is a crucial aspect of growth and development. Ferroptosis, which was postulated roughly ten years ago, is a mode of cell death that differs from apoptosis, au...

    Authors: Qi Zhang, Yuhao Luo, Lin Peng, Xi Rong, Yingxue Liu, Jiafu Li and Jing Luo
    Citation: Cell & Bioscience 2023 13:226
  32. Neurodegenerative diseases seriously affect patients’ physical and mental health, reduce their quality of life, and impose a heavy burden on society. However, their treatment remains challenging. Therefore, ex...

    Authors: Ziyan Hu, Yifan Luo, Jinxi Zhu, Danling Jiang, Zhenzhong Luo, Lidong Wu, Jin Li, Shengliang Peng and Jialing Hu
    Citation: Cell & Bioscience 2023 13:225
  33. The most common site of metastasis in breast cancer is the bone, where the balance between osteoclast-mediated bone resorption and osteoblast-mediated bone formation is disrupted. This imbalance causes osteoly...

    Authors: Shenkangle Wang, Wenxin Wu, Xixi Lin, Kevin Matthew Zhang, QingLiang Wu, Mingpeng Luo and Jichun Zhou
    Citation: Cell & Bioscience 2023 13:224
  34. Activation of the Wnt pathway has been linked to colorectal cancer (CRC). Previous reports suggest that Wnt3a can activate p38. Besides, p38α feeds into the canonical Wnt/β-catenin pathway by inhibiting GSK3β ...

    Authors: Martina Lepore Signorile, Candida Fasano, Giovanna Forte, Katia De Marco, Paola Sanese, Vittoria Disciglio, Elisabetta Di Nicola, Antonino Pantaleo, Cristiano Simone and Valentina Grossi
    Citation: Cell & Bioscience 2023 13:223
  35. The scarcity of pluripotent stem cells poses a major challenge to the clinical application, given ethical and biosafety considerations. While germline stem cells commit to gamete differentiation throughout lif...

    Authors: Rui Wei, Xiaoyu Zhang, Xiaoxiao Li, Jian Wen, Hongyang Liu, Jiqiang Fu, Li Li, Wenyi Zhang, Zhen Liu, Yang Yang and Kang Zou
    Citation: Cell & Bioscience 2023 13:222
  36. Aberrant stress granules (SGs) are emerging as prime suspects in the nucleation of toxic protein aggregates. Understanding the molecular networks linked with aggregation-prone proteins (prion protein, synuclei...

    Authors: Neelam Younas, Saima Zafar, Tayyaba Saleem, Leticia Camila Fernandez Flores, Abrar Younas, Matthias Schmitz and Inga Zerr
    Citation: Cell & Bioscience 2023 13:221
  37. Metabolic homeostasis is closely related to early impairment of cell fate determination and embryo development. The protein kinase mechanistic target of rapamycin (mTOR) is a key regulator of cellular metaboli...

    Authors: Chiyuan Ma, Qin Li, Yuxin Yang, Lei Ge, Jiaxuan Cai, Juan Wang, Maoxian Zhu, Yue Xiong, Wenya Zhang, Jingtong Xie, Yujing Cao, Huashan Zhao, Qing Wei, Chen Huang, Junchao Shi, Jian V. Zhang…
    Citation: Cell & Bioscience 2023 13:219
  38. l-ascorbic acid (Asc) plays a pivotal role in regulating various biological processes, including somatic cell reprogramming, through multiple pathways. However, it remains unclear whether Asc regulates reprogra.....

    Authors: Lining Liang, Meiai He, Yixin Zhang, Chenchen Wang, Zhaohui Qin, Qian Li, Tingting Yang, Fei Meng, Yusheng Zhou, Haofei Ge, Weining Song, Shiyu Chen, Linna Dong, Qiwen Ren, Changpeng Li, Lin Guo…
    Citation: Cell & Bioscience 2023 13:218
  39. The role of mast cells (MCs) in colorectal cancer (CRC) remains unclear, and a comprehensive single-cell study on CRC MCs has not been conducted. This study used a multi-omics approach, integrating single-cell...

    Authors: Zhenyu Xie, Liaoran Niu, Gaozan Zheng, Kunli Du, Songchen Dai, Ruikai Li, Hanjun Dan, Lili Duan, Hongze Wu, Guangming Ren, Xinyu Dou, Fan Feng, Jian Zhang and Jianyong Zheng
    Citation: Cell & Bioscience 2023 13:217
  40. Primary biliary cholangitis (PBC) is an autoimmune liver disease. The aetiology of PBC remains unclear, and its pathogenesis is complex. Animal models are essential to clarify the pathogenesis of PBC and explo...

    Authors: Xu Wang, Yi Wei, Yanlei Yang, Yunjiao Yang, Haolong Li, Yongzhe Li, Fengchun Zhang and Li Wang
    Citation: Cell & Bioscience 2023 13:214
  41. Abnormalities in the 5-HT system and synaptic plasticity are hallmark features of schizophrenia. Previous studies suggest that the human endogenous retrovirus W family envelope (ERVWE1) is an influential risk ...

    Authors: Xiulin Wu, Lianzhong Liu, Xing Xue, Xuhang Li, Kexin Zhao, Jiahang Zhang, Wenshi Li, Wei Yao, Shuang Ding, Chen Jia and Fan Zhu
    Citation: Cell & Bioscience 2023 13:213
  42. Prostate cancer is a leading cause of cancer-related deaths among men worldwide. Docetaxel chemotherapy has proven effective in improving overall survival in patients with castration-resistant prostate cancer ...

    Authors: Bisheng Cheng, Lingfeng Li, Yongxin Wu, Tianlong Luo, Chen Tang, Qiong Wang, Qianghua Zhou, Jilin Wu, Yiming Lai, Dingjun Zhu, Tao Du and Hai Huang
    Citation: Cell & Bioscience 2023 13:211

    The Correction to this article has been published in Cell & Bioscience 2024 14:17