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  1. Content type: Research

    Mesenchymal stem cells (MSCs) have been extensively explored as a promising therapeutic agent in the field of bone tissue engineering due to their osteogenic differentiation ability. In this study, the osteoge...

    Authors: Chongyang Shen, Chuan Yang, Shijun Xu and Hai Zhao

    Citation: Cell & Bioscience 2019 9:17

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  2. Content type: Research

    Neoadjuvant chemotherapy (NAC) induces a pathological complete response (pCR) in ~ 30% of patients with breast cancer. However, aberrant DNA methylation alterations are frequent events during breast cancer pro...

    Authors: Yumei Luo, Juan Huang, Yi Tang, Xitu Luo, Lingxia Ge, Xiujie Sheng, Xiaofang Sun, Yaoyong Chen and Detu Zhu

    Citation: Cell & Bioscience 2019 9:16

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  3. Content type: Research

    More than the two decades, the question of whether vitamin D has a role in cancer frequency, development, and death has been premeditated in detail. Colorectal, breast, and prostate cancers have been a scrupul...

    Authors: Suhail Razak, Tayyaba Afsar, Ali Almajwal, Iftikhar Alam and Sarwat Jahan

    Citation: Cell & Bioscience 2019 9:15

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  4. Content type: Research

    Breast cancer was dangerous to women health. A growing number of evidences indicate that long non-coding RNAs (lncRNAs) have many functions in the development and progression of breast cancer and may serve as ...

    Authors: Xiaopeng Hu, Yun Liu, Yaying Du, Teng Cheng and Wenfei Xia

    Citation: Cell & Bioscience 2019 9:14

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  5. Content type: Research

    Psychological and physical stress can either enhance or suppress immune functions depending on a variety of factors such as duration and severity of stressful situation. Chronic stress exerts a significantly s...

    Authors: Anna Qin, Ting Zhong, Huajiao Zou, Xiaoya Wan, Bifeng Yao, Xinbin Zheng and Deling Yin

    Citation: Cell & Bioscience 2019 9:13

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  6. Content type: Research

    Proliferative vitreoretinopathy (PVR) is a severe blinding complication of retinal detachment surgery. Increasing evidence demonstrate that PVR is associated with oxidative stress. Scutellarin is a natural fla...

    Authors: Xin Hu, Xiaofang Wu, Bo Zhao and Yongyi Wang

    Citation: Cell & Bioscience 2019 9:12

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  7. Content type: Research

    The aim of this study was to investigate the role of long non-coding RNAs (LncRNAs) antisense non-coding RNA in the INK4 locus (ANRIL) in anti-inflammation of rhein in uric acid nephropathy (UAN) rats.

    Authors: Jiacai Hu, Daochun Wang, Hao Wu, Zhijie Yang, Na Yang and Junjun Dong

    Citation: Cell & Bioscience 2019 9:11

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  8. Content type: Research

    Transmembrane protein 108 (Tmem108) is a risk gene of psychiatric diseases including schizophrenia, bipolar disorder and major depression disorder. However, the pathophysiological mechanisms of Tmem108 are lar...

    Authors: Zheng Yu, Dong Lin, Yanzi Zhong, Bin Luo, Shengsheng Liu, Erkang Fei, Xinsheng Lai, Suqi Zou and Shunqi Wang

    Citation: Cell & Bioscience 2019 9:9

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  9. Content type: Research

    Calcium signaling are conserved from invertebrates to vertebrates and plays critical roles in many molecular mechanisms of embryogenesis and postnatal development. As a critical component of the signaling path...

    Authors: Rui Feng, Xin Zhou, Wei Zhang, Tao Pu, Yuting Sun, Rong Yang, Dan Wang, Xiaofei Zhang, Yingfeng Gao, Zhenlu Cai, Yu Liang, Qiuxia Yu, Yajun Wu, Xinjuan Lei, Zhijia Liang, Odell Jones…

    Citation: Cell & Bioscience 2019 9:8

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  10. Content type: Review

    Cellular senescence is a major hurdle for primary cell-based tissue engineering and regenerative medicine. Telomere erosion, oxidative stress, the expression of oncogenes and the loss of tumor suppressor genes...

    Authors: Yiming Wang, Song Chen, Zuoqin Yan and Ming Pei

    Citation: Cell & Bioscience 2019 9:7

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  11. Content type: Research

    TRAF3 is known as a central mediator of type I interferon (IFN) induction by various pattern recognition receptors, but the in vivo function of TRAF3 in host defense against viral infection is poorly defined d...

    Authors: Xiaoping Xie, Jin Jin, Lele Zhu, Zuliang Jie, Yanchuan Li, Baoyu Zhao, Xuhong Cheng, Pingwei Li and Shao-Cong Sun

    Citation: Cell & Bioscience 2019 9:5

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  12. Content type: Research

    Cancer patients treated with chemotherapy often experience a rapid decline of blood neutrophils, a dose-limiting side effect called chemotherapy-induced neutropenia. This complication brings about dose reducti...

    Authors: Jinseon Jeong, Yong-Jae Kim, Do Young Lee, Byoung-Gon Moon, Ki-Young Sohn, Sun Young Yoon and Jae Wha Kim

    Citation: Cell & Bioscience 2019 9:4

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  13. Content type: Research

    The PI3K/Akt and the STAT3 pathways are functionally associated in many tumor types. Both in vitro and in vivo studies have revealed that either biochemical or genetic manipulation of the STAT3 pathway activit...

    Authors: María Elisa Picco, María Victoria Castro, María Josefina Quezada, Gastón Barbero, María Belén Villanueva, Natalia Brenda Fernández, Hyungsoo Kim and Pablo Lopez-Bergami

    Citation: Cell & Bioscience 2019 9:3

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  14. Content type: Research

    To determine whether and how exosomes from human umbilical vein endothelial cells (HUVEC-Exos) regulates vascular smooth muscle cells (VSMCs) calcification/senescence in high glucose condition.

    Authors: Shuang Li, Jun-Kun Zhan, Yan-Jiao Wang, Xiao Lin, Jia-Yu Zhong, Yi Wang, Pan Tan, Jie-Yu He, Xing-Jun Cui, Yi-Yin Chen, Wu Huang and You-Shuo Liu

    Citation: Cell & Bioscience 2019 9:1

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  15. Content type: Research

    Sialic acids represent common terminal residues on numerous mammalian glycoconjugates, thereby influencing e.g. lumen formation in developing blood vessels. Interestingly, besides monosialylated also polysialy...

    Authors: Sebastian Strubl, Uwe Schubert, Andrea Kühnle, Alexander Rebl, Negah Ahmadvand, Silvia Fischer, Klaus T. Preissner and Sebastian P. Galuska

    Citation: Cell & Bioscience 2018 8:64

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  16. Content type: Review

    Increasing evidence indicates that long non-coding RNAs (lncRNAs) regulate gene or protein expression; however, their function in the progression of hepatic fibrosis remains unclear. Hepatic fibrosis is a cont...

    Authors: Hu Peng, Lin-Yan Wan, Jia-Jie Liang, Yan-Qiong Zhang, Wen-Bing Ai and Jiang-Feng Wu

    Citation: Cell & Bioscience 2018 8:63

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  17. Content type: Research

    Evaluating the risk category of gastrointestinal stromal tumors (GISTs) is crucial for predicting prognosis and choosing treatment strategies, and tumor metastasis usually represent poor prognosis. Tumor necro...

    Authors: Zequn Li, Wei Zhang, Yi Li, Shougen Cao, Shanglong Liu, Liang Ning, Xuelong Jiao, Zimin Liu, Xiaoming Xing, Yujun Li and Yanbing Zhou

    Citation: Cell & Bioscience 2018 8:62

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  18. Content type: Research

    Increasing evidence has suggested the involvement of long non-coding RNA taurine upregulated gene 1 (TUG1) in chemoresistance of cancer treatment. However, its function and molecular mechanisms in esophageal s...

    Authors: Caihui Xu, Yinmou Guo, Haiyan Liu, Gongbin Chen, Yanju Yan and Teng Liu

    Citation: Cell & Bioscience 2018 8:61

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  19. Content type: Research

    Microglia activation is a crucial event in neurodegenerative disease. The depression of microglial inflammatory response is considered a promising therapeutic strategy. NFκB signaling, including IKK/IκB phosph...

    Authors: Huanhuan Wang, Wenhai Huang, Meihao Liang, Yingying Shi, Chixiao Zhang, Qin Li, Meng Liu, Yikai Shou, Hongping Yin, Xiaozheng Zhu, Xiaoyan Sun, Yu Hu and Zhengrong Shen

    Citation: Cell & Bioscience 2018 8:60

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  20. Content type: Research

    It has been reported that CBP/p300-Interacting Transactivator with glutamic acid [E]/aspartic acid [D]-rich C-terminal domain 1 (CITED1) is overexpressed in papillary thyroid cancer (PTC). However, the functio...

    Authors: Hai Li, Hongyu Guan, Yan Guo, Weiwei Liang, Liehua Liu, Xiaoying He, Weijian Ke, Xiaopei Cao, Haipeng Xiao and Yanbing Li

    Citation: Cell & Bioscience 2018 8:57

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  21. Content type: Review

    Contrary to Warburg’s hypothesis, mitochondrial oxidative phosphorylation (OXPHOS) contributes significantly to fueling cancer cells. Several recent studies have demonstrated that radiotherapy-resistant and ch...

    Authors: Sarada Preeta Kalainayakan, Keely E. FitzGerald, Purna Chaitanya Konduri, Chantal Vidal and Li Zhang

    Citation: Cell & Bioscience 2018 8:56

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  22. Content type: Research

    Fine osseointegration is the basis of long-term survival of implant. In our previous study, we observed a strong correlation between hyperlipidemia and compromised osseointegration. MicroRNA-29a-3p (miR-29a-3p...

    Authors: Fei Liu, Zhifeng Wang, Fangfang Liu, Jinzhao Xu, Qibo Liu, Kaifeng Yin and Jing Lan

    Citation: Cell & Bioscience 2018 8:55

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  23. Content type: Research

    Mycobacterium smegmatis, a rapidly growing non-tuberculosis mycobacterium, is a good model for studying the pathogenesis of tuberculosis because of its genetic similarity to Mycobacterium tuberculosis (Mtb). Macr...

    Authors: Seon-Hwa Kim, Soo-Na Cho, Yun-Ji Lim, Ji-Ae Choi, Junghwan Lee, Dam Go and Chang-Hwa Song

    Citation: Cell & Bioscience 2018 8:52

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  24. Content type: Research

    We investigated the inhibitory effect of pantoprazole on signal transducer and activator of transcription 3 (STAT3) activity and invasiveness of gastric adenocarcinoma cells, and the role of SH2-containing pro...

    Authors: Jin Sung Koh, Moon Kyung Joo, Jong-Jae Park, Hyo Soon Yoo, Byung Il Choi, Beom Jae Lee, Hoon Jai Chun and Sang Woo Lee

    Citation: Cell & Bioscience 2018 8:50

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  25. Content type: Research

    Zika virus (ZIKV) has recently become a major matter of concern since its association with microcephaly cases in newborns was determined. From then on, ZIKV has been untiringly studied, and several scientific ...

    Authors: Mohamed Ziad Dabaja, Estela de Oliveira Lima, Diogo Noin de Oliveira, Tatiane Melina Guerreiro, Carlos Fernando Odir Rodrigues Melo, Karen Noda Morishita, Marcelo Lancellotti, Ana Lucia Tasca Gois Ruiz, Gisele Goulart, Diego Andreazzi Duarte and Rodrigo Ramos Catharino

    Citation: Cell & Bioscience 2018 8:47

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  26. Content type: Research

    Tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 (TIPE2 or TNFAIP8L2) is a newly described negative immune regulator and is closely associated with various tumors. However, the expression and roles o...

    Authors: Wenyu Jia, Zequn Li, Junyu Chen, Lei Sun, Chuanqian Liu, Shaping Wang, Jingwei Chi, Jun Niu and Hong Lai

    Citation: Cell & Bioscience 2018 8:49

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  27. Content type: Research

    Bone regenerative heterodimeric bone morphogenetic protein 2/7 (BMP2/7) enhances but all-trans retinoic acid (ATRA) inhibits osteoclastogenesis. However, the effect of ATRA on physiological and/or BMP2/7-induc...

    Authors: Wenjuan Bi, Yi Liu, Jing Guo, Zhen Lin, Jinsong Liu, Miao Zhou, Daniel Wismeijer, Janak L. Pathak and Gang Wu

    Citation: Cell & Bioscience 2018 8:48

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  28. Content type: Research

    Diabetes mellitus is associated with an increased risk in diabetic cardiomyopathy (DCM) that is distinctly not attributed to co-morbidities with other vasculature diseases. To date, while dysregulation of calc...

    Authors: Khampaseuth Thapa, Kai Connie Wu, Aishwarya Sarma, Eric M. Grund, Angela Szeto, Armando J. Mendez, Stephane Gesta, Vivek K. Vishnudas, Niven R. Narain and Rangaprasad Sarangarajan

    Citation: Cell & Bioscience 2018 8:45

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  29. Content type: Research

    Notch signaling is mainly regulated by Notch1 during development of chicken germ stem cells; however, the molecular mechanisms that contribute to generation of these germ stem cells have not been thoroughly in...

    Authors: Qisheng Zuo, Chen Zhang, Kai Jin, Jin Jing, Changhua Sun, Mahmoud F. Ahmed, Jiuzhou Song, Yani Zhang, Guohong Chen and Bichun Li

    Citation: Cell & Bioscience 2018 8:40

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  30. Content type: Research

    This study investigated the role of HSP70 in modulating intestinal γδ T cells’ Th17 response in Trichinella spiralis-induced PI-IBS mice model.

    Authors: Zhoutao He, Xiaoning Sun, Zhichao Ma, Jiao Fu, Baili Huang, Fujin Liu, Yi Chen, Taozhi Deng, Xiangyang Han, Deming Sun and Cheng Lan

    Citation: Cell & Bioscience 2018 8:38

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  31. Content type: Research

    As an important danger signal, the presence of DNA in cytoplasm triggers potent immune responses. Cyclic GMP-AMP synthase (cGAS) is a recently characterized key sensor for cytoplasmic DNA. The engagement of cG...

    Authors: Zhao-Shan Liu, Zi-Yu Zhang, Hong Cai, Ming Zhao, Jie Mao, Jiang Dai, Tian Xia, Xue-Min Zhang and Tao Li

    Citation: Cell & Bioscience 2018 8:35

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  32. Content type: Letter to the Editor

    Two studies have recently focused on adult heart regeneration in Xenopus. While we reported on cardiac myogenic regeneration in Xenopus tropicalis after injury, Marshall and colleagues found no regeneration in an...

    Authors: Souqi Liao, Wenyan Dong, Hui Zhao, Ruijin Huang, Xufeng Qi and Dongqing Cai

    Citation: Cell & Bioscience 2018 8:32

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