Skip to main content

Articles

Page 3 of 17

  1. Acute liver failure (ALF) is associated with a high mortality rate, and there are still no effective treatments except liver transplantation and artificial liver therapies. This study aimed to determine the ef...

    Authors: Guohua Lou, Aichun Li, Yelei Cen, Qin Yang, Tianbo Zhang, Jinjin Qi, Zhi Chen and Yanning Liu

    Citation: Cell & Bioscience 2021 11:9

    Content type: Research

    Published on:

  2. The evasion from apoptosis is a common strategy adopted by most tumors, and inhibitors of apoptosis proteins (IAPs) are among the most studied molecular and therapeutic targets. BIRC3 (cellular IAP2) and BIRC5 (s...

    Authors: Raffaele Frazzi

    Citation: Cell & Bioscience 2021 11:8

    Content type: Review

    Published on:

  3. Mesenchymal stem cells (MSCs) have been proved to drive castration resistant prostate cancer (CRPC). In this study, we aim to investigate the contribution of MSCs to the development of docetaxel resistance in ...

    Authors: Yang Yu, Fu-han Yang, Wen-tao Zhang, Ya-dong Guo, Lin Ye and Xu-dong Yao

    Citation: Cell & Bioscience 2021 11:7

    Content type: Research

    Published on:

  4. Current studies have enlightened the rosy prospects of human pluripotent stem cell (hPSC)-derived mesenchymal stem/stromal cells (MSCs) in regenerative medicine. However, systematic investigation of their sign...

    Authors: Leisheng Zhang, Yimeng Wei, Ying Chi, Dengke Liu, Sijun Yang, Zhongchao Han and Zongjin Li

    Citation: Cell & Bioscience 2021 11:6

    Content type: Research

    Published on:

  5. Goserelin is an effective alternative to surgery or estrogen therapy in prostate cancer palliation, and possibly to ovariectomy in premenopausal breast cancer. However, not all users of goserelin can benefit f...

    Authors: Yue Zhao, Huimin Sun, Jianzhong Zheng, Chen Shao and Dongwei Zhang

    Citation: Cell & Bioscience 2021 11:5

    Content type: Research

    Published on:

  6. The fertilizing spermatozoon is a highly specialized cell that selects from millions along the female tract until the oocyte. The paternal components influence the oocyte activation during fertilization and ar...

    Authors: Mohammad Ishraq Zafar, Shi Lu and Honggang Li

    Citation: Cell & Bioscience 2021 11:4

    Content type: Review

    Published on:

  7. Hepatic stellate cells (HSCs) are activated in response to liver injury with TIF1γ-suppression, leading to liver fibrosis. Here, we examined the mechanism how reduction of TIF1γ in HSCs induces damage on hepat...

    Authors: Injoo Hwang, Eun Ju Lee, Hyomin Park, Dodam Moon and Hyo-Soo Kim

    Citation: Cell & Bioscience 2021 11:3

    Content type: Research

    Published on:

  8. Interleukin-22 (IL-22), a member of the IL-10 family of cytokines, is produced by a number of immune cells involved in the immune microenvironment of the body. IL-22 plays its pivotal roles by binding to the I...

    Authors: Xiuyun Xuan, Lin Zhang, Chunxia Tian, Ting Wu, Haihua Ye, Juanmei Cao, Fangqi Chen, Yan Liang, Huilan Yang and Changzheng Huang

    Citation: Cell & Bioscience 2021 11:2

    Content type: Review

    Published on:

  9. Drug resistance is a major impediment in cancer therapy which strongly reduces the efficiency of anti-cancer drugs. Exosomes are extracellular vesicles with cup or spherical shape with a size range of 40–150 n...

    Authors: Mostafa Mostafazadeh, Nasser Samadi, Houman Kahroba, Behzad Baradaran, Sanya Haiaty and Mohammad Nouri

    Citation: Cell & Bioscience 2021 11:1

    Content type: Review

    Published on:

  10. The angiotensin-converting enzyme 2 (ACE2) is the host functional receptor for the new virus SARS-CoV-2 causing Coronavirus Disease 2019. ACE2 is expressed in 72 different cell types. Some factors that can aff...

    Authors: Miriam Marlene Medina-Enríquez, Sandra Lopez-León, José Alberto Carlos-Escalante, Zuleika Aponte-Torres, Angelica Cuapio and Talia Wegman-Ostrosky

    Citation: Cell & Bioscience 2020 10:148

    Content type: Review

    Published on:

  11. Increased reactive oxygen species (ROS) production by arsenic treatment in solid tumors showed to be effective to sensitize cancer cells to chemotherapies. Arsenic nano compounds are known to increase the ROS ...

    Authors: Wei Zhou, Meiyue Liu, Xia Li, Peng Zhang, Jiong Li, Yue Zhao, Guogui Sun and Weimin Mao

    Citation: Cell & Bioscience 2020 10:146

    Content type: Research

    Published on:

    The Correction to this article has been published in Cell & Bioscience 2021 11:22

  12. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Aihua Bao, Aying Ma, Hui Zhang, Lihua Qiao, Suqin Ben, Xin Zhou and Min Zhang

    Citation: Cell & Bioscience 2020 10:145

    Content type: Correction

    Published on:

    The original article was published in Cell & Bioscience 2020 10:120

  13. Accumulating evidence shows that Parkinson’s disease is negatively associated with colon cancer risk, indicating that Parkinson’s disease family proteins may be involved in the initiation of colon cancer. Here...

    Authors: Qian Chen, Li Zhong, Chao Zhou, Yan Feng, Quan-xing Liu, Dong Zhou, Xiao Lu, Guang-Sheng Du, Dan Jian, Hao Luo, Dong Wang, Hong Zheng and Yuan Qiu

    Citation: Cell & Bioscience 2020 10:144

    Content type: Research

    Published on:

  14. Enhancer of zeste homolog 2 (EZH2), as a main component of Polycomb Repressive Complex 2, catalyzes histone H3K27me3 to silence its target gene expression. EZH2 upregulation results in cancer development and p...

    Authors: Zhongwei Li, Minle Li, Diandian Wang, Pingfu Hou, Xintian Chen, Sufang Chu, Dafei Chai, Junnian Zheng and Jin Bai

    Citation: Cell & Bioscience 2020 10:143

    Content type: Review

    Published on:

  15. The expression of Kelch-like protein 18 (KLHL18) in non-small cell lung cancer (NSCLC) is lower than that in normal lung tissue according to the Gene Expression Profiling Interactive Analysis database. KLHL18 ...

    Authors: Xizi Jiang, Yitong XU, Hongjiu Ren, Jun Jiang, Muli Wudu, Qiongzi Wang, Jingqian Guan, Hongbo Su, Yao Zhang, Bo Zhang, Yuanzi Guo, Yujiao Hu, Lihong Jiang, Zongang Liu, Huanxi Wang, Yu Cheng…

    Citation: Cell & Bioscience 2020 10:139

    Content type: Research

    Published on:

  16. Proliferation markers, such as proliferating cell nuclear antigen (PCNA), Ki-67, and thymidine kinase 1 (TK1), have potential as diagnostic tools and as prognostic factors in assessing cancer treatment and dis...

    Authors: Eliza E. Bitter, Michelle H. Townsend, Rachel Erickson, Carolyn Allen and Kim L. O’Neill

    Citation: Cell & Bioscience 2020 10:138

    Content type: Review

    Published on:

  17. Macrophages that accumulate in atherosclerotic plaques contribute to progression of the lesions to more advanced and complex plaques. Although iron deposition was found in human atherosclerotic plaques, clinic...

    Authors: Jing Cai, Meng Zhang, Yutong Liu, Huihui Li, Longcheng Shang, Tianze Xu, Zhipeng Chen, Fudi Wang, Tong Qiao and Kuanyu Li

    Citation: Cell & Bioscience 2020 10:137

    Content type: Research

    Published on:

  18. Epilepsy is characterized by the typical symptom of seizure, and anti-seizure medications are the main therapeutic method in clinical, but the effects of these therapy have not been satisfactory. To find a bet...

    Authors: Zheng Yu, Meiying Zhang, Bin Luo, Hongyang Jing, Yue Yu, Shunqi Wang and Shiwen Luo

    Citation: Cell & Bioscience 2020 10:135

    Content type: Research

    Published on:

  19. Some chemokine receptors referred to as atypical chemokine receptors (ACKRs) are thought to non-signaling decoys because of their inability to activate typical G-protein signaling pathways. CXCR7, also known a...

    Authors: Huong Thi Nguyen, Arfaxad Reyes-Alcaraz, Hyo Jeong Yong, Lan Phuong Nguyen, Hee-Kyung Park, Asuka Inoue, Cheol Soon Lee, Jae Young Seong and Jong-Ik Hwang

    Citation: Cell & Bioscience 2020 10:134

    Content type: Research

    Published on:

  20. Colostrum quality is a vital factor in mortality and growth performance for piglets. Lactoferrin is an immuno-active milk protein that contributes to the formation of a protective layer above intestinal mucosa...

    Authors: Xiaosong Han, Yang Gao, Guanglei Li, Youcai Xiong, Changzhi Zhao, Jinxue Ruan, Yunlong Ma, Xinyun Li, Changchun Li, Shuhong Zhao and Shengsong Xie

    Citation: Cell & Bioscience 2020 10:133

    Content type: Letter to the Editor

    Published on:

  21. Aberration of estrogen (E2) and/or progesterone (P4) signaling pathways affects expression of their target genes, which may lead to failure of embryo implantation and following pregnancy. Although many target gen...

    Authors: Hee Kyoung Park, So Hee Park, Miji Lee, Gyeong Ryeong Kim, Mira Park, Seung Chel Yang, Yeon Sun Kim, Hyunjung J. Lim, Hye-Ryun Kim and Haengseok Song

    Citation: Cell & Bioscience 2020 10:132

    Content type: Research

    Published on:

  22. Lysosomes are an important component of the inner membrane system and participate in numerous cell biological processes, such as macromolecular degradation, antigen presentation, intracellular pathogen destruc...

    Authors: Tao Tang, Ze-yu Yang, Di Wang, Xian-yan Yang, Jun Wang, Lin Li, Qian Wen, Lei Gao, Xiu-wu Bian and Shi-cang Yu

    Citation: Cell & Bioscience 2020 10:131

    Content type: Review

    Published on:

  23. Mesenchymal stem cells (MSCs) represent a promising treatment option for acute kidney injury (AKI). The main drawbacks of MSCs therapy, including the lack of specific homing after systemic infusion and early c...

    Authors: Song Zhou, Yu-ming Qiao, Yong-guang Liu, Ding Liu, Jian-min Hu, Jun Liao, Min Li, Ying Guo, Li-pei Fan, Liu-Yang Li and Ming Zhao

    Citation: Cell & Bioscience 2020 10:130

    Content type: Research

    Published on:

  24. Both testis and ovary can be produced sequentially in an individual with the same genome when sex reversal occurs in the teleost Monopterus albus, and epigenetic modification is supposed to be involved in gonadal...

    Authors: Xin Wang, Fengling Lai, Jun Xiong, Wang Zhu, Bifeng Yuan, Hanhua Cheng and Rongjia Zhou

    Citation: Cell & Bioscience 2020 10:129

    Content type: Research

    Published on:

  25. The tumor microenvironment (TME) is a complex multicellular functional compartment that includes fibroblasts, myofibroblasts, endothelial cells, immune cells, and extracellular matrix (ECM) elements. The micro...

    Authors: Jie Zhang, Chaoyu Gu, Qianqian Song, Mengqi Zhu, Yuqing Xu, Mingbing Xiao and Wenjie Zheng

    Citation: Cell & Bioscience 2020 10:127

    Content type: Review

    Published on:

  26. Mesenchymal stem cells (MSCs) isolated from bone marrow have different developmental origins, including neural crest. MSCs can differentiate into neural progenitor-like cells (NPCs) under the influence of bFGF...

    Authors: Amir Ali Khan, Tee Jong Huat, Abdullah Al Mutery, Ahmed Taher El-Serafi, Hassen Hadj Kacem, Sallam Hasan Abdallah, Muhammed Faruque Reza, Jafri Malin Abdullah and Hasnan Jaafar

    Citation: Cell & Bioscience 2020 10:126

    Content type: Research

    Published on:

  27. Asthma is one of the main intractable diseases recognized by the international medical community. The current widely used bronchodilators for asthma—β2-adrenal receptor agonists—have limited therapeutic effect...

    Authors: Ping Zhao, Jia Liu, Qian Ming, Di Tian, Jingwen He, Ziwei Yang, Jinhua Shen, Qing-Hua Liu and Xinzhou Yang

    Citation: Cell & Bioscience 2020 10:125

    Content type: Research

    Published on:

  28. Glioblastoma (GBM) is an immunosuppressive, highly vascular and devastating malignant brain tumor. Even with progressive combination treatment that includes surgery, radiotherapy, and chemotherapy, the prognos...

    Authors: Qing Zhang, Junwen Zhang, Yifu Tian, Guidong Zhu, Sisi Liu and Fusheng Liu

    Citation: Cell & Bioscience 2020 10:124

    Content type: Research

    Published on:

  29. Risk stratifications for endometrial carcinoma (EC) depend on histopathology and molecular pathology. Histopathological risk stratification lacks reproducibility, neglects heterogeneity and contributes little ...

    Authors: Yuan Li, Jiaqi Li, Ensong Guo, Jia Huang, Guangguang Fang, Shaohua Chen, Bin Yang, Yu Fu, Fuxia Li, Zizhuo Wang, Rourou Xiao, Chen Liu, Yuhan Huang, Xue Wu, Funian Lu, Lixin You…

    Citation: Cell & Bioscience 2020 10:122

    Content type: Research

    Published on:

  30. Acute lung injury (ALI) is a serious disease with highly morbidity and mortality that causes serious health problems worldwide. Atypical mitogen activated protein kinases (MAPKs) play critical roles in the dev...

    Authors: Ling Mao, Ya Zhou, Longqing Chen, Lin Hu, Shiming Liu, Wen Zheng, Juanjuan Zhao, Mengmeng Guo, Chao Chen, Zhixu He and Lin Xu

    Citation: Cell & Bioscience 2020 10:121

    Content type: Research

    Published on:

  31. Heat shock protein (HSP) 20 is a molecular chaperone that exerts multiple protective functions in various kinds of tissues. However, the expression of HSP20 and its specific functions in airway epithelial cell...

    Authors: Aihua Bao, Aying Ma, Hui Zhang, Lihua Qiao, Suqin Ben, Xin Zhou and Min Zhang

    Citation: Cell & Bioscience 2020 10:120

    Content type: Research

    Published on:

    The Correction to this article has been published in Cell & Bioscience 2020 10:145

  32. Alternative splicing (AS), a crucial post-transcriptional regulatory mechanism in expanding the coding capacities of genomes and increasing the diversity of proteins, still faces various challenges in the spli...

    Authors: Nan Zhang, Ping Zhang, Ying Chen, Shifeng Lou, Hanqing Zeng and Jianchuan Deng

    Citation: Cell & Bioscience 2020 10:118

    Content type: Research

    Published on:

  33. Destruction and death of neurons can lead to neurodegenerative diseases. One possible way to treat neurodegenerative diseases and damage of the nervous system is replacing damaged and dead neurons by cell tran...

    Authors: Ziran Xu, Shengnan Su, Siyan Zhou, Wentao Yang, Xin Deng, Yingying Sun, Lisha Li and Yulin Li

    Citation: Cell & Bioscience 2020 10:116

    Content type: Review

    Published on:

  34. Thyroid cancer (TC) is the most common type of endocrine malignancy and its incidence is increasing over years. Conventional surgery, radiotherapy and chemotherapy are difficult to improve the significant effe...

    Authors: Guohong Zhao, Jianqin Kang, Guanghui Xu, Jing Wei, Xiaoguang Wang, Xiaorui Jing, Lan Zhang, Aili Yang, Kai Wang, Jue Wang, Li Wang, Junfeng Hou, Qingquan Liu, Kai Jiao and Bin Gao

    Citation: Cell & Bioscience 2020 10:115

    Content type: Research

    Published on:

  35. Phloretin is isolated from apple trees and could increase lipolysis in 3T3-L1 adipocytes. Previous studies have found that phloretin could prevent obesity in mice. In this study, we investigated whether phlore...

    Authors: Chian-Jiun Liou, Shu-Ju Wu, Szu-Chuan Shen, Li-Chen Chen, Ya-Ling Chen and Wen-Chung Huang

    Citation: Cell & Bioscience 2020 10:114

    Content type: Research

    Published on:

  36. Angiogenesis is a critical step in the growth of pancreatic neuroendocrine tumors (PNETs) and may be a selective target for PNET therapy. However, PNETs are robustly resistant to current anti-angiogenic therap...

    Authors: Xi Luo, Jiang-yi He, Jie Xu, Shao-yi Hu, Bang-hui Mo, Qiu-xia Shu, Can Chen, Yu-zhu Gong, Xiao-long Zhao, Gan-feng Xie and Song-tao Yu

    Citation: Cell & Bioscience 2020 10:113

    Content type: Research

    Published on:

  37. Spinal cord injury (SCI) is the damage to the spinal cord that can lead to temporary or permanent loss of function due to injury to the nerve. The SCI patients are often associated with poor quality of life.

    Authors: Ling Ling Liau, Qi Hao Looi, Wui Chuen Chia, Thayaalini Subramaniam, Min Hwei Ng and Jia Xian Law

    Citation: Cell & Bioscience 2020 10:112

    Content type: Review

    Published on:

  38. Ten-eleven translocation (TET) proteins, encoding dioxygenase for DNA hydroxymethylation, are important players in nervous system development and disease. In addition to their proverbial enzymatic role, TET pr...

    Authors: Ming Zhang, Kaixiang Zhang, Jian Wang, Yuming Liu, Guangxin Liu, Weilin Jin, Shengxi Wu and Xianghui Zhao

    Citation: Cell & Bioscience 2020 10:110

    Content type: Research

    Published on:

  39. Alzheimer’s disease (AD) is a neurodegenerative disease that leads to progressive loss of memory and dementia. The pathological hallmarks of AD include extracellular accumulation of amyloid-β peptides forming ...

    Authors: Hariharakrishnan Chidambaram, Rashmi Das and Subashchandrabose Chinnathambi

    Citation: Cell & Bioscience 2020 10:109

    Content type: Review

    Published on: