Noble J, Munro CA, Prasad VS, Midha R. Analysis of upper and lower extremity peripheral nerve injuries in a population of patients with multiple injuries. J Trauma. 1998;45(1):116–22.
CAS
PubMed
Google Scholar
Scheib J, Hoke A. Advances in peripheral nerve regeneration. Nat Rev Neurol. 2013;9(12):668–76.
CAS
PubMed
Google Scholar
Wang L, Sanford MT, Xin Z, Lin G, Lue TF. Role of Schwann cells in the regeneration of penile and peripheral nerves. Asian J Androl. 2015;17(5):776–82.
CAS
PubMed
PubMed Central
Google Scholar
Abe N, Cavalli V. Nerve injury signaling. Curr Opin Neurobiol. 2008;18(3):276–83.
CAS
PubMed
PubMed Central
Google Scholar
Yuan H, Zhang J, Liu H, Li Z. The protective effects of resveratrol on Schwann cells with toxicity induced by ethanol in vitro. Neurochem Int. 2013;63(3):146–53.
CAS
PubMed
Google Scholar
Komiyama A, Novicki DL, Suzuki K. Adhesion and proliferation are enhanced in vitro in Schwann cells from nerve undergoing Wallerian degeneration. J Neurosci Res. 1991;29(3):308–18.
CAS
PubMed
Google Scholar
Bhatheja K, Field J. Schwann cells: origins and role in axonal maintenance and regeneration. Int J Biochem Cell Biol. 2006;38(12):1995–9.
CAS
PubMed
Google Scholar
Torigoe K, Tanaka HF, Takahashi A, Awaya A, Hashimoto K. Basic behavior of migratory Schwann cells in peripheral nerve regeneration. Exp Neurol. 1996;137(2):301–8.
CAS
PubMed
Google Scholar
Guertin AD, Zhang DP, Mak KS, Alberta JA, Kim HA. Microanatomy of axon/glial signaling during Wallerian degeneration. J Neurosci. 2005;25(13):3478–87.
CAS
PubMed
PubMed Central
Google Scholar
Yang DP, Zhang DP, Mak KS, Bonder DE, Pomeroy SL, Kim HA. Schwann cell proliferation during Wallerian degeneration is not necessary for regeneration and remyelination of the peripheral nerves: axon-dependent removal of newly generated Schwann cells by apoptosis. Mol Cell Neurosci. 2008;38(1):80–8.
CAS
PubMed
PubMed Central
Google Scholar
Wong KM, Babetto E, Beirowski B. Axon degeneration: make the Schwann cell great again. Neural Regen Res. 2017;12(4):518–24.
PubMed
PubMed Central
Google Scholar
Jessen KR, Mirsky R, Lloyd AC. Schwann cells: development and role in nerve repair. Cold Spring Harb Perspect Biol. 2015;7(7):a020487.
PubMed
PubMed Central
Google Scholar
Jessen KR, Mirsky R. The repair Schwann cell and its function in regenerating nerves. J Physiol. 2016;594(13):3521–31.
CAS
PubMed
PubMed Central
Google Scholar
Sodek J, Ganss B, McKee MD. Osteopontin. Crit Rev Oral Biol Med. 2000;11(3):279–303.
CAS
PubMed
Google Scholar
Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S, et al. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science. 2000;287(5454):860–4.
CAS
PubMed
Google Scholar
Rangaswami H, Bulbule A, Kundu GC. Osteopontin: role in cell signaling and cancer progression. Trends Cell Biol. 2006;16(2):79–877.
CAS
PubMed
Google Scholar
Flores ME, Norgård M, Heinegård D, Reinholt FP, Andersson G. RGD-directed attachment of isolated rat osteoclasts to osteopontin, bone sialoprotein, and fibronectin. Exp Cell Res. 1992;201(2):526–30.
CAS
PubMed
Google Scholar
Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS. Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest. 2001;107(9):1055–61.
CAS
PubMed
PubMed Central
Google Scholar
Kazanecki CC, Uzwiak DJ, Denhardt DT. Control of osteopontin signaling and function by post-translational phosphorylation and protein folding. J Cell Biochem. 2007;102(4):912–24.
CAS
PubMed
Google Scholar
Jander S, Bussini S, Neuen-Jacob E, Bosse F, Menge T, Muller HW, et al. Osteopontin: a novel axon-regulated Schwann cell gene. J Neurosci Res. 2002;67(2):156–66.
CAS
PubMed
Google Scholar
Wright MC, Mi R, Connor E, Reed N, Vyas A, Alspalter M, et al. Novel roles for osteopontin and clusterin in peripheral motor and sensory axon regeneration. J Neurosci. 2014;34(5):1689–700.
CAS
PubMed
PubMed Central
Google Scholar
Küry P, Zickler P, Stoll G, Hartung H-P, Jander S. Osteopontin, a macrophage-derived matricellular glycoprotein, inhibits axon outgrowth. FASEB J. 2005;19(3):398–400.
PubMed
Google Scholar
Liu X, Sun Y, Li H, Li Y, Li M, Yuan Y, et al. Effect of Spp1 on nerve degeneration and regeneration after rat sciatic nerve injury. BMC Neurosci. 2017;18(1):30.
PubMed
PubMed Central
Google Scholar
Li J, Zhang Z, Wang J, Du S, Yao D, Cao R, et al. Protein kinase cα promotes proliferation and migration of Schwann cells by activating ERK signaling pathway. Neuroscience. 2020;433:94–107.
CAS
PubMed
Google Scholar
Uede T. Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases. Pathol Int. 2011;61(5):265–80.
CAS
PubMed
Google Scholar
Chakraborty G, Jain S, Kundu GC. Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms. Cancer Res. 2008;68(1):152–61.
CAS
PubMed
Google Scholar
Shevde LA, Samant RS. Role of osteopontin in the pathophysiology of cancer. Matrix Biol J Int Soc Matrix Biol. 2014;37:131–41.
CAS
Google Scholar
Luo X, Ruhland MK, Pazolli E, Lind AC, Stewart SA. Osteopontin stimulates preneoplastic cellular proliferation through activation of the MAPK pathway. Mol Cancer Res. 2011;9(8):1018–29.
CAS
PubMed
Google Scholar
Kim JM, Kim MY, Lee K, Jeong D. Distinctive and selective route of PI3K/PKCα-PKCΔ/RhoA-Rac1 signaling in osteoclastic cell migration. Mol Cell Endocrinol. 2016;437:261–7.
CAS
PubMed
Google Scholar
Yamamiya M, Tanabe S, Muramatsu R. Microglia promote the proliferation of neural precursor cells by secreting osteopontin. Biochem Biophys Res Commun. 2019;513(4):841–5.
CAS
PubMed
Google Scholar
Milner R, Wilby M, Nishimura S, Boylen K, Edwards G, Fawcett J, et al. Division of labor of Schwann cell integrins during migration on peripheral nerve extracellular matrix ligands. Dev Biol. 1997;185(2):215–28.
CAS
PubMed
Google Scholar
Sherman LS, Rizvi TA, Karyala S, Ratner N. CD44 enhances neuregulin signaling by Schwann cells. J Cell Biol. 2000;150(5):1071–84.
CAS
PubMed
PubMed Central
Google Scholar
Kim JM, Noh EM, Kwon KB, Kim JS, You YO, Hwang JK, et al. Curcumin suppresses the TPA-induced invasion through inhibition of PKCα-dependent MMP-expression in MCF-7 human breast cancer cells. Phytomedicine. 2012;19(12):1085–92.
CAS
PubMed
Google Scholar
Schytte GN, Christensen B, Bregenov I, Kjoge K, Scavenius C, Petersen SV, et al. FAM20C phosphorylation of the RGDSVVYGLR motif in osteopontin inhibits interaction with the αvβ3 integrin. J Cell Biochem. 2020. https://doi.org/10.1002/jcb.29708.
Article
PubMed
Google Scholar
Marsh BCL, Kerr NC, Isles N, Denhardt DT, Wynick D. Osteopontin expression and function within the dorsal root ganglion. NeuroReport. 2007;18(2):153–7.
CAS
PubMed
PubMed Central
Google Scholar
Misawa H, Hara M, Tanabe S, Niikura M, Moriwaki Y, Okuda T. Osteopontin is an alpha motor neuron marker in the mouse spinal cord. J Neurosci Res. 2012;90(4):732–42.
CAS
PubMed
Google Scholar
Duan X, Qiao M, Bei F, Kim IJ, He Z, Sanes JR. Subtype-specific regeneration of retinal ganglion cells following axotomy: effects of osteopontin and mTOR signaling. Neuron. 2015;85(6):1244–56.
CAS
PubMed
PubMed Central
Google Scholar
Selvaraju R, Bernasconi L, Losberger C, Graber P, Kadi L, Avellana-Adalid V, et al. Osteopontin is upregulated during in vivo demyelination and remyelination and enhances myelin formation in vitro. Mol Cell Neurosci. 2004;25(4):707–21.
CAS
PubMed
Google Scholar
Michie AM, Nakagawa R. The link between PKCα regulation and cellular transformation. Immunol Lett. 2005;96(2):155–62.
CAS
PubMed
Google Scholar
Ogata T, Yamamoto S-I, Nakamura K, Tanaka S. Signaling axis in Schwann cell proliferation and differentiation. Mol Neurobiol. 2006;33(1):51–62.
CAS
PubMed
Google Scholar
Seo TB, Oh M-J, You B-G, Kwon K-B, Chang I-A, Yoon J-H, et al. ERK1/2-mediated Schwann cell proliferation in the regenerating sciatic nerve by treadmill training. J Neurotrauma. 2009;26(10):1733–44.
PubMed
Google Scholar
Zhang W, Liu HT. MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res. 2002;12(1):9–18.
CAS
PubMed
Google Scholar
Tapinos N, Rambukkana A. Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli. Proc Natl Acad Sci USA. 2005;102(26):9188–93.
CAS
PubMed
Google Scholar
Sheu JY, Kulhanek DJ, Eckenstein FP. Differential patterns of ERK and STAT3 phosphorylation after sciatic nerve transection in the rat. Exp Neurol. 2000;166(2):392–402.
CAS
PubMed
Google Scholar
Agthong S, Kaewsema A, Tanomsridejchai N, Chentanez V. Activation of MAPK ERK in peripheral nerve after injury. BMC neuroscience. 2006;7:45.
CAS
PubMed
PubMed Central
Google Scholar
Kim J, Erikson DW, Burghardt RC, Spencer TE, Wu G, Bayless KJ, et al. Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells. Matrix Biol. 2010;29(5):369–82.
CAS
PubMed
Google Scholar
Zhao X, Liu F, Jin H, Li R, Wang Y, Zhang W, et al. Involvement of PKCα and ERK1/2 signaling pathways in EGCG’s protection against stress-induced neural injuries in Wistar rats. Neuroscience. 2017;346:226–37.
CAS
PubMed
PubMed Central
Google Scholar
Strasser A, O'Connor L, Dixit VM. Apoptosis signaling. Annu Rev Biochem. 2000;69:217–45.
CAS
PubMed
Google Scholar
Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 1993;74(4):609–19.
CAS
PubMed
Google Scholar
Strasser A, Vaux DL. Viewing BCL2 and cell death control from an evolutionary perspective. Cell Death Differ. 2018;25(1):13–20.
CAS
PubMed
Google Scholar
Zhu L, Hao J, Cheng M, Zhang C, Huo C, Liu Y, et al. Hyperglycemia-induced Bcl-2/Bax-mediated apoptosis of Schwann cells via mTORC1/S6K1 inhibition in diabetic peripheral neuropathy. Exp Cell Res. 2018;367(2):186–95.
CAS
PubMed
Google Scholar
Teramoto H, Castellone MD, Malek RL, Letwin N, Frank B, Gutkind JS, et al. Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12. Oncogene. 2005;24(3):489–501.
CAS
PubMed
Google Scholar
Weintraub AS, Giachelli CM, Krauss RS, Almeida M, Taubman MB. Autocrine secretion of osteopontin by vascular smooth muscle cells regulates their adhesion to collagen gels. Am J Pathol. 1996;149(1):259–72.
CAS
PubMed
PubMed Central
Google Scholar
Geissinger E, Weisser C, Fischer P, Schartl M, Wellbrock C. Autocrine stimulation by osteopontin contributes to antiapoptotic signalling of melanocytes in dermal collagen. Cancer Res. 2002;62(16):4820–8.
CAS
PubMed
Google Scholar
Jessen KR, Mirsky R. Why do Schwann cells survive in the absence of axons? Ann NY Acad Sci. 1999;883(1):109–15.
PubMed
Google Scholar
Cheng L, Esch FS, Marchionni MA, Mudge AW. Control of Schwann cell survival and proliferation: autocrine factors and neuregulins. Molecular Cell Neurosci. 1998;12(3):141–56.
CAS
Google Scholar
Jiang R, Prell C, Lonnerdal B. Milk osteopontin promotes brain development by up-regulating osteopontin in the brain in early life. FASEB J. 2019;33(2):1681–94.
CAS
PubMed
Google Scholar
Caers J, Gunthert U, De Raeve H, Van Valckenborgh E, Menu E, Van Riet I, et al. The involvement of osteopontin and its receptors in multiple myeloma cell survival, migration and invasion in the murine 5T33MM model. Br J Haematol. 2006;132(4):469–77.
CAS
PubMed
Google Scholar
Dai J, Peng L, Fan K, Wang H, Wei R, Ji G, et al. Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells. Oncogene. 2009;28(38):3412–22.
CAS
PubMed
Google Scholar
Woodhoo A, Alonso MBD, Droggiti A, Turmaine M, D'Antonio M, Parkinson DB, et al. Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity. Nat Neurosci. 2009;12(7):839–47.
CAS
PubMed
PubMed Central
Google Scholar