Guicciardi ME, Gores GJ: Bile acid-mediated hepatocyte apoptosis and cholestatic liver disease. Dig Liver Dis. 2002, 34: 387-392. 10.1016/S1590-8658(02)80033-0
Article
CAS
PubMed
Google Scholar
Reichel C, Meier-Abt PJ: Cholestatic liver diseases. Ther Umsch. 1997, 54: 639-644.
CAS
PubMed
Google Scholar
Karvonen J, Kairisto V, Gronroos JM: Stone or stricture as a cause of extrahepatic cholestasis–do liver function tests predict the diagnosis?. Clin Chem Lab Med. 2006, 44: 1453-1456.
Article
CAS
PubMed
Google Scholar
Zhangxue H, Min G, Jinning Z, Yuan S, Li W, Huapei S, Rui L, Chunyu Z: Glycochenodeoxycholate induces rat alveolar epithelial type II cell death and inhibits surfactant secretion in vitro. Free Radic Biol Med. 2012, 53: 122-128. 10.1016/j.freeradbiomed.2012.04.027
Article
PubMed
Google Scholar
Heuman DM, Mills AS, McCall J, Hylemon PB, Pandak WM, Vlahcevic ZR: Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat. Gastroenterology. 1991, 100: 203-211.
CAS
PubMed
Google Scholar
Schmucker DL, Ohta M, Kanai S, Sato Y, Kitani K: Hepatic injury induced by bile salts: correlation between biochemical and morphological events. Hepatology. 1990, 12: 1216-1221. 10.1002/hep.1840120523
Article
CAS
PubMed
Google Scholar
Schoemaker MH, Gommans WM, de la Conde Rosa L, Homan M, Klok P, Trautwein C, van Goor H, Poelstra K, Haisma HJ, Jansen PL, Moshage H: Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation. J Hepatol. 2003, 39: 153-161. 10.1016/S0168-8278(03)00214-9
Article
CAS
PubMed
Google Scholar
Patel T, Bronk SF, Gores GJ: Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes. J Clin Invest. 1994, 94: 2183-2192. 10.1172/JCI117579
Article
PubMed Central
CAS
PubMed
Google Scholar
Czaja MJ: Functions of autophagy in hepatic and pancreatic physiology and disease. Gastroenterology. 2011, 140: 1895-1908. 10.1053/j.gastro.2011.04.038
Article
PubMed Central
PubMed
Google Scholar
Yorimitsu T, Klionsky DJ: Autophagy: molecular machinery for self-eating. Cell Death Differ. 2005, 12 (Suppl 2): 1542-1552.
Article
PubMed Central
CAS
PubMed
Google Scholar
Moreau K, Luo S, Rubinsztein DC: Cytoprotective roles for autophagy. Curr Opin Cell Biol. 2010, 22: 206-211. 10.1016/j.ceb.2009.12.002
Article
PubMed Central
CAS
PubMed
Google Scholar
Kuma A, Matsui M, Mizushima N: LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization. Autophagy. 2007, 3: 323-328. 10.4161/auto.4012
Article
CAS
PubMed
Google Scholar
Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, Bray K, Reddy A, Bhanot G, Gelinas C, Dipaola RS, Karantza-Wadsworth V, White E: Autophagy suppresses tumorigenesis through elimination of p62. Cell. 2009, 137: 1062-1075. 10.1016/j.cell.2009.03.048
Article
PubMed Central
CAS
PubMed
Google Scholar
Narendra D, Kane LA, Hauser DN, Fearnley IM, Youle RJ: p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy. 2010, 6: 1090-1106. 10.4161/auto.6.8.13426
Article
PubMed Central
CAS
PubMed
Google Scholar
Manley S, Williams JA, Ding WX: Role of p62/SQSTM1 in liver physiology and pathogenesis. Exp Biol Med (Maywood). 2013, 238: 525-538. 10.1177/1535370213489446
Article
Google Scholar
Arroyo DS, Gaviglio EA, Peralta Ramos JM, Bussi C, Rodriguez-Galan MC, Iribarren P: Autophagy in inflammation, infection, neurodegeneration and cancer. Int Immunopharmacol. 2014, 18: 55-65. 10.1016/j.intimp.2013.11.001
Article
PubMed Central
CAS
PubMed
Google Scholar
Ding WX, Li M, Chen X, Ni HM, Lin CW, Gao W, Lu B, Stolz DB, Clemens DL, Yin XM: Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice. Gastroenterology. 2010, 139: 1740-1752. 10.1053/j.gastro.2010.07.041
Article
PubMed Central
CAS
PubMed
Google Scholar
Igusa Y, Yamashina S, Izumi K, Inami Y, Fukada H, Komatsu M, Tanaka K, Ikejima K, Watanabe S: Loss of autophagy promotes murine acetaminophen hepatotoxicity. J Gastroenterol. 2012, 47: 433-443. 10.1007/s00535-011-0500-0
Article
CAS
PubMed
Google Scholar
Ni HM, Bockus A, Boggess N, Jaeschke H, Ding WX: Activation of autophagy protects against acetaminophen-induced hepatotoxicity. Hepatology. 2012, 55: 222-232. 10.1002/hep.24690
Article
PubMed Central
CAS
PubMed
Google Scholar
Singh R, Kaushik S, Wang Y, Xiang Y, Novak I, Komatsu M, Tanaka K, Cuervo AM, Czaja MJ: Autophagy regulates lipid metabolism. Nature. 2009, 458: 1131-1135. 10.1038/nature07976
Article
PubMed Central
CAS
PubMed
Google Scholar
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T: LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 2000, 19: 5720-5728. 10.1093/emboj/19.21.5720
Article
PubMed Central
CAS
PubMed
Google Scholar
Yerushalmi B, Dahl R, Devereaux MW, Gumpricht E, Sokol RJ: Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Hepatology. 2001, 33: 616-626. 10.1053/jhep.2001.22702
Article
CAS
PubMed
Google Scholar
Sokol RJ, Winklhofer-Roob BM, Devereaux MW, McKim JM: Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids. Gastroenterology. 1995, 109: 1249-1256. 10.1016/0016-5085(95)90585-5
Article
CAS
PubMed
Google Scholar
Maes M, Mihaylova I, Kubera M, Uytterhoeven M, Vrydags N, Bosmans E: Increased 8-hydroxy-deoxyguanosine, a marker of oxidative damage to DNA, in major depression and myalgic encephalomyelitis/chronic fatigue syndrome. Neuro Endocrinol Lett. 2009, 30: 715-722.
CAS
PubMed
Google Scholar
Lin CW, Zhang H, Li M, Xiong X, Chen X, Dong XC, Yin XM: Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice. J Hepatol. 2013, 58: 993-999. 10.1016/j.jhep.2013.01.011
Article
PubMed Central
CAS
PubMed
Google Scholar
Osna NA, Thomes PG, Jr TM: Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis. World J Gastroenterol. 2011, 17: 2507-2514. 10.3748/wjg.v17.i20.2507
Article
PubMed Central
PubMed
Google Scholar
Sun K, Xie X, Liu Y, Han Z, Zhao X, Cai N, Zhang S, Song J, Wei L: Autophagy lessens ischemic liver injury by reducing oxidative damage. Cell Biosci. 2013, 3: 26. 10.1186/2045-3701-3-26
Article
PubMed Central
CAS
PubMed
Google Scholar
Yun N, Cho HI, Lee SM: Impaired autophagy contributes to hepatocellular damage during ischemia/reperfusion: heme oxygenase-1 as a possible regulator. Free Radic Biol Med. 2014, 68: 168-177.
Article
CAS
PubMed
Google Scholar
Rautou PE, Mansouri A, Lebrec D, Durand F, Valla D, Moreau R: Autophagy in liver diseases. J Hepatol. 2010, 53: 1123-1134. 10.1016/j.jhep.2010.07.006
Article
CAS
PubMed
Google Scholar
Shiomi M, Miyamae M, Takemura G, Kaneda K, Inamura Y, Onishi A, Koshinuma S, Momota Y, Minami T, Figueredo VM: Induction of autophagy restores the loss of sevoflurane cardiac preconditioning seen with prolonged ischemic insult. Eur J Pharmacol. 2014, 724: 58-66.
Article
CAS
PubMed
Google Scholar
Loos B, Genade S, Ellis B, Lochner A, Engelbrecht AM: At the core of survival: autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury. Exp Cell Res. 2011, 317: 1437-1453. 10.1016/j.yexcr.2011.03.011
Article
CAS
PubMed
Google Scholar
Ding ZB, Hui B, Shi YH, Zhou J, Peng YF, Gu CY, Yang H, Shi GM, Ke AW, Wang XY, Song K, Dai Z, Shen YH, Fan J: Autophagy activation in hepatocellular carcinoma contributes to the tolerance of oxaliplatin via reactive oxygen species modulation. Clin Cancer Res. 2011, 17: 6229-6238. 10.1158/1078-0432.CCR-11-0816
Article
CAS
PubMed
Google Scholar
Kanki T: Nix, a receptor protein for mitophagy in mammals. Autophagy. 2010, 6: 433-435. 10.4161/auto.6.3.11420
Article
CAS
PubMed
Google Scholar
Tsai LY, Lee KT, Liu TZ: Evidence for accelerated generation of hydroxyl radicals in experimental obstructive jaundice of rats. Free Radic Biol Med. 1998, 24: 732-737. 10.1016/S0891-5849(97)00330-4
Article
CAS
PubMed
Google Scholar