Fig. 2
From: PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders
GO and KEGG analysis of differential expression genes (DEGs) in 45,XO embryoids during hPGCLC differentiation from hiPSCs. a Venn diagram showing number of DEGs (both up- and down-regulation) in hPGCLCs from embryoids during specification among 45,XO, 46,XX, and 46,XY. b Gene Ontology (GO) analysis of up-regulated DEGs among 45,XO, 46,XX, and 46,XY. X-axis indicated the catalogs of biological process, cellular component, and molecular function. Y-axis on the left indicated the -Log (P value). c KEGG analysis of up-regulated DEGs. The cycle sizes represented the actual number of DEGs that were classified in a particular pathway. X-axis indicated the ratio of genes in the particular pathway. d GO analysis of down-regulated DEGs. X-axis indicated the catalogs of biological process, cellular component, and molecular function. Y-axis indicated the -Log (P value). e KEGG analysis of down-regulated DEGs