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Fig. 1 | Cell & Bioscience

Fig. 1

From: Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits

Fig. 1

Effects of perinatal intermittent hypoxia on cellular mechanisms in P12 mice. A Quantification of ROS production in the whole cerebellum of control (N) or hypoxic (IH) P12 mice. B Significant RT-qPCR results reflecting the regulation of the expression of genes involved in the production of ROS in the whole cerebellum of control (N) or hypoxic (IH) P12 mice. C Significant RT-qPCR results reflecting the regulation of the expression of genes associated to apoptosis in the whole cerebellum of control (N) or hypoxic (IH) P12 mice. D Enzymatic activity of caspase-3/7 (left) and density of cleaved caspase 3 positive cells (right) in the whole cerebellum of control (N) or hypoxic (IH) P12 mice. For B and C, the number of animals was 15 for the N group and 10 for the IH group. For A and D, the total number of animals in each experimental group is indicated under the boxplots and represented by diamond shapes, while the transparent dots indicate individual data points. Exact p-values are indicated above the plot. IH: intermittent hypoxia condition; N: normoxia condition; P12: postnatal day 12; ROS: reactive oxygen species

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Cell & Bioscience

ISSN: 2045-3701

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