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Fig.6 | Cell & Bioscience

Fig.6

From: cGAS inhibition alleviates Alu RNA-induced immune responses and cytotoxicity in retinal pigmented epithelium

Fig.6

EGCG/RSVL suppresses Alu RNA-induced cell death. a Annexin V/PI analysis by flow cytometry of ARPE-19 cells transfected with Alu RNA (4 μg mL−1) for 48 h or non-transfected (Ctrl), following a 3-h pretreatment of EGCG (20 μM). b The percentage of dead cells in (a) was quantified. c Annexin V/PI analysis by flow cytometry of ARPE-19 cells transfected with Alu RNA (4 μg mL−1) for 48 h, following a 3-h pretreatment of RSVL (40 μM). d The percentage of dead cells in (c) was quantified. Data are mean ± s.e.m. of three independent experiments, **P < 0.01, ***P < 0.001, two-tailed t-test (b and d)

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