Table 5 miRNAs in clinical trials
From: Small RNAs in eucaryotes: new clues for amplifying microRNA benefits
miRNA | Drug name | Disease |
|---|---|---|
miR-34 | MRX34 | Multiple cancers |
miR-92 | MRG110 MGN-6114 | Heart failure/wound healing |
miR-16 | mesomiR-1 | Mesothelioma, lung cancer |
miR-122 | Miravirsen RG101 | Hepatitis C virus |
miR-29 | MRG201 MGN4220 | Keloid, fibrous scar tissue formation |
miR-21 | RG012 | Alport syndrome |
miR-155 | Cobomarsen (MRG-106) | T-cell lymphoma/mycosis fungoides |
miR-143/145 | MGN2677 | Vascular disease |
miR-451 | MGN-4893 | Polycythemia vera |
miR-378 | MGN5804 | Cardiometabolic disease |
miR-15/miR-195 | MGN-1374 | Post-myocardial infarction remodelling |
miR-208 | MGN9103 | Heart failure |