Open Access

Erratum to: A new paradigm of DNA synthesis: three-metal-ion catalysis

Cell & Bioscience20177:32

https://doi.org/10.1186/s13578-017-0159-1

Received: 15 June 2017

Accepted: 15 June 2017

Published: 20 June 2017

The original article was published in Cell & Bioscience 2016 6:51

Erratum to: Cell Biosci (2016) 6:51 DOI 10.1186/s13578-016-0118-2

Upon publication of the original article [1], it was noticed that the Fig. 2 is incorrect. This has now been acknowledged and corrected in this erratum. The correct Fig. 2 has been shown below.
Fig. 2

Comparison of the initiation of phosphoryltransfer in two- versus three-metal-ion catalysis. a In three-metal-ion catalysis, the C-site metal ion initiates the reaction by breaking the existing phosphodiester bond in dNTP and thus drives the phosphoryltransfer reaction. A well-aligned native 3′-OH is required for capture of the C-site metal ion and its deprotonation is a result of the reaction. b In two-metal-ion catalysis, the reaction starts by de-protonation of the 3′-OH (nucleophile), which activates nucleophilic attack and leads to breakage of the existing phosphodiester bond in dNTP

Notes

Declarations

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Laboratory of Molecular Biology, NIDDK, National Institutes of Health

Reference

  1. Yang W, Weng PJ, Gao Y. A new paradigm of DNA synthesis: three-metal-ion catalysis. Cell Biosci. 2016;6(1):51. doi:10.1186/s13578-016-0118-2.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© The Author(s) 2017

Advertisement