Figure 3
From: Proteomic analysis of mismatch repair-mediated alkylating agent-induced DNA damage response
Heat map of differential changes in protein phosphorylation between TK6 and MT1. Phosphorylation sites with the following criteria were extracted for heat map: (1) same phosphosite was quantified in both MNNG-treated TK6 and MT1 nuclear fraction; (2) the phosphosite was up- or down-regulated in at least one cell type. The protein accession numbers and phosphosites were labeled, and all shown phosphoproteins were classified by their biological processes based on Gene Ontology (GO) annotation. Some phosphoproteins may exist in several different biological processes.