Skip to main content



Page 11 of 11

  1. Content type: Review

    The TGFβ and Ras-MAPK pathways play critical roles in cell development and cell cycle regulation, as well as in tumor formation and metastasis. In the absence of cellular transformation, these pathways operate...

    Authors: Douglas A Chapnick, Lisa Warner, Jennifer Bernet, Timsi Rao and Xuedong Liu

    Citation: Cell & Bioscience 2011 1:42

    Published on:

  2. Content type: Review

    Smad proteins are classified in different groups based on their functions in mediating transforming growth factor β (TGFβ) superfamily components. Smad1/5/8 mainly mediate bone morphogenetic proteins (BMP) pat...

    Authors: Gangwen Han and Xiao-Jing Wang

    Citation: Cell & Bioscience 2011 1:41

    Published on:

  3. Content type: Research

    It remains unclear whether retroviruses can encode and express an intragenomic microRNA (miRNA). Some have suggested that processing by the Drosha and Dicer enzymes might preclude the viability of a replicatin...

    Authors: Zachary Klase, Laurent Houzet and Kuan-Teh Jeang

    Citation: Cell & Bioscience 2011 1:38

    Published on:

  4. Content type: Review

    Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of heat. It is held that in mammals, long-term surplus food inta...

    Authors: Xuan Yao, Shifang Shan, Ying Zhang and Hao Ying

    Citation: Cell & Bioscience 2011 1:35

    Published on:

  5. Content type: Research

    Cancer cells possess unique metabolic phenotypes that are determined by their underlying oncogenic pathways. Activation of the PI3K/Akt/mTOR signaling cascade promotes glycolysis and leads to glucose-dependenc...

    Authors: Xiuyun Jiang, Heidi L Kenerson and Raymond S Yeung

    Citation: Cell & Bioscience 2011 1:34

    Published on:

  6. Content type: Research

    Despite detailed in vivo knowledge of glycolytic enolases and many bacterial non-enolase members of the superfamily, little is known about the in vivo function of vertebrate non-enolase enolase superfamily member...

    Authors: Steve Finckbeiner, Pin-Joe Ko, Blake Carrington, Raman Sood, Kenneth Gross, Bruce Dolnick, Janice Sufrin and Paul Liu

    Citation: Cell & Bioscience 2011 1:32

    Published on:

  7. Content type: Review

    Adult organ-specific stem cells are essential for organ homeostasis and repair in adult vertebrates. The intestine is one of the best-studied organs in this regard. The intestinal epithelium undergoes constant...

    Authors: Yun-Bo Shi, Takashi Hasebe, Liezhen Fu, Kenta Fujimoto and Atsuko Ishizuya-Oka

    Citation: Cell & Bioscience 2011 1:30

    Published on:

  8. Content type: Review

    The epithelial to mesenchymal transition (EMT) plays crucial roles in the formation of the body plan and also in the tumor invasion process. In addition, EMT also causes disruption of cell-cell adherence, loss...

    Authors: Yingying Jing, Zhipeng Han, Shanshan Zhang, Yan Liu and Lixin Wei

    Citation: Cell & Bioscience 2011 1:29

    Published on:

  9. Content type: Research

    Laribacter hongkongensis is a Gram-negative, sea gull-shaped rod associated with community-acquired gastroenteritis. The bacterium has been found in diverse freshwater environments including fish, frogs and drink...

    Authors: Susanna KP Lau, Rachel YY Fan, Gilman KM Wong, Jade LL Teng, Kong-Hung Sze, Herman Tse, Kwok-Yung Yuen and Patrick CY Woo

    Citation: Cell & Bioscience 2011 1:28

    Published on:

  10. Content type: Research

    Human papillomavirus (HPV) pseudovirions have recently been shown to deliver DNA efficiently in vivo, resulting in the priming of antigen-specific CD8+ T cells in vaccinated mice. In the current study, we compare...

    Authors: Shiwen Peng, Barbara Ma, Shu-Hsia Chen, Chien-Fu Hung and TC Wu

    Citation: Cell & Bioscience 2011 1:26

    Published on:

  11. Content type: Review

    The Inhibitor of Growth (ING) proteins represent a type II tumor suppressor family comprising five conserved genes, ING1 to ING5. While ING1, ING2 and ING3 proteins are stable components of the mSIN3a-HDAC comple...

    Authors: Susann Ludwig, Alexandra Klitzsch and Aria Baniahmad

    Citation: Cell & Bioscience 2011 1:25

    Published on:

  12. Content type: Review

    Thyroid hormone (TH) is involved in many biological functions such as animal development, cell differentiation, etc. Variation and/or disruption of plasma TH level often led to abnormalities and physiological ...

    Authors: Shao-Chung Hsia, Gautam R Bedadala and Matthew D Balish

    Citation: Cell & Bioscience 2011 1:24

    Published on:

  13. Content type: Research

    Laribacter hongkongensis is associated with community-acquired gastroenteritis and traveler's diarrhea and it can reside in human, fish, frogs and water. In this study, we performed an in-depth annotation of the ...

    Authors: Susanna KP Lau, Rachel YY Fan, Tom CC Ho, Gilman KM Wong, Alan KL Tsang, Jade LL Teng, Wenyang Chen, Rory M Watt, Shirly OT Curreem, Herman Tse, Kwok-Yung Yuen and Patrick CY Woo

    Citation: Cell & Bioscience 2011 1:22

    Published on:

  14. Content type: Research

    Hemorrhage increases inducible nitric oxide synthase (iNOS) and depletes ATP levels in various tissues. Previous studies have shown that geldanamycin, an inducer of heat shock protein 70kDa (HSP-70) and inhibi...

    Authors: Juliann G Kiang, Neil G Agravante, Joan T Smith and Phillip D Bowman

    Citation: Cell & Bioscience 2011 1:21

    Published on:

  15. Content type: Research

    Lithium, a drug that has long been used to treat bipolar disorder and some other human pathogenesis, has recently been shown to stimulate neural precursor growth. However, the involved mechanism is not clear. ...

    Authors: Zhaoxia Qu, Dongming Sun and Wise Young

    Citation: Cell & Bioscience 2011 1:18

    Published on:

  16. Content type: Research

    Laribacter hongkongensis is associated with community-acquired gastroenteritis and traveler's diarrhea. In this study, we performed an in-depth annotation of the genes in its genome related to the various steps i...

    Authors: Susanna KP Lau, Gilman KM Wong, Alan KL Tsang, Jade LL Teng, Rachel YY Fan, Herman Tse, Kwok-Yung Yuen and Patrick CY Woo

    Citation: Cell & Bioscience 2011 1:17

    Published on:

  17. Content type: Research

    Laribacter hongkongensis is associated with community-acquired gastroenteritis and traveler's diarrhea. In this study, we performed an in-depth annotation of the genes and pathways of the general metabolism of L....

    Authors: Shirly O Curreem, Jade L Teng, Herman Tse, Kwok-Yung Yuen, Susanna K Lau and Patrick C Woo

    Citation: Cell & Bioscience 2011 1:16

    Published on:

  18. Content type: Methodology

    This study describes the successful delivery of helper-dependent adenoviral vectors to the mouse retina with long term and robust levels of reporter expression in the retina without apparent adverse effects. S...

    Authors: Linda Wu, Simon Lam, Huibi Cao, Rui Guan, Rongqi Duan, Derek van der Kooy, Rod Bremner, Robert S Molday and Jim Hu

    Citation: Cell & Bioscience 2011 1:15

    Published on:

  19. Content type: Research

    Tissue inhibitor of metalloproteinase 1 (TIMP-1), which is thought to be produced mainly by activated hepatic stellate cells and Kupffer cells in the liver, plays a pivotal role in matrix remodeling during liv...

    Authors: Hua Wang, Fouad Lafdil, Lei Wang, Shi Yin, Dechun Feng and Bin Gao

    Citation: Cell & Bioscience 2011 1:14

    Published on:

  20. Content type: Research

    Breast cancer, the most common malignancy in women, still holds many secrets. The causes for non-hereditary breast cancer are still unknown. To elucidate any role for circulating naturally secreted proteins, a...

    Authors: Sofie C Van Huffel, Jill M Tham, XiaoQian Zhang, KohPang Lim, ChunXuan Yang, YikLoo Tan, Felicia Ong, Ian Lee and WanJin Hong

    Citation: Cell & Bioscience 2011 1:13

    Published on:

  21. Content type: Research

    Haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. Although the exact pathophysiology of haloperidol extrapyramidal symptoms are not known, the role...

    Authors: Joachim Perera, Joon Heng Tan, S Jeevathayaparan, Srikumar Chakravarthi and Nagaraja Haleagrahara

    Citation: Cell & Bioscience 2011 1:12

    Published on:

  22. Content type: Research

    During DNA replication or repair, disease-associated (CAG)n/(CTG)n expansion can result from formation of hairpin structures in the repeat tract of the newly synthesized or nicked DNA strand. Recent studies ident...

    Authors: Caixia Hou, Tianyi Zhang, Lei Tian, Jian Huang, Liya Gu and Guo-Min Li

    Citation: Cell & Bioscience 2011 1:11

    Published on:

  23. Content type: Research

    Age-related macular degeneration (AMD) is the leading cause of vision loss in elderly people over 60. The pathogenesis is still unclear. It has been suggested that lysosomal stress may lead to drusen formation...

    Authors: Patrick M Chen, Zoë J Gombart and Jeff W Chen

    Citation: Cell & Bioscience 2011 1:10

    Published on:

  24. Content type: Review

    Metastasis accounts for 90% of cancer-related mortality. Brain metastases generally present during the late stages in the natural history of cancer progression. Recent advances in cancer treatment and manageme...

    Authors: Chenyu Zhang and Dihua Yu

    Citation: Cell & Bioscience 2011 1:8

    Published on:

  25. Content type: Review

    Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the two major forms of primary liver cancers (PLC), accounting for approximately 90% and 5% respectively. The incidence of each is i...

    Authors: Mia Kumar, Xuelian Zhao and Xin Wei Wang

    Citation: Cell & Bioscience 2011 1:5

    Published on:

  26. Content type: Research

    MicroRNA (miRNA) molecules are potent mediators of post-transcriptional gene silencing that are emerging to be critical in the regulation of innate and adaptive immunity.

    Authors: Chih-Ping Mao, Liangmei He, Ya-Chea Tsai, Shiwen Peng, Tae Heung Kang, Xiaowu Pang, Archana Monie, Chien-Fu Hung and T-C Wu

    Citation: Cell & Bioscience 2011 1:3

    Published on:

  27. Content type: Editorial

    This Editorial briefly introduces the Society of Chinese Bioscientists in America (SCBA) to readers of Cell & Bioscience.

    Authors: Kuan-Teh Jeang

    Citation: Cell & Bioscience 2011 1:2

    Published on: