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Fig. 4 | Cell & Bioscience

Fig. 4

From: Ivermectin increases striatal cholinergic activity to facilitate dopamine terminal function

Fig. 4

IVM effects on striatal cholinergic interneurons. A Representative image of glass capillary electrode connected to a DS CIN. B Representative traces of CIN firing rate before (left) and after IVM application (right). C Time course of CIN normalized frequency showing IVM is increasing DS CIN firing rate. D Ivermectin increases CIN firing rate frequency. E Action potential frequency variance (Var.) was increased in some but not all neurons, and group changes were not statistically significant. Asterisks *,** indicate significance levels p < 0.05, p < 0.01 compared to ACSF pre-treatment

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