Klotho | General population |
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Unadjusted model | Adjusted model |
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HR (95% CI) | P-value | HR (95% CI) | P-value |
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T1 | Ref. | Â | Â | Â |
T2 | 0.648 (0.529, 0.793) |  < 0.001 | 0.741 (0.598, 0.919) | 0.006 |
T3 | 0.746 (0.635, 0.877) |  < 0.001 | 0.913 (0.757, 1.101) | 0.340 |
P–t |  | 0.001 |  | 0.385 |
Continuous | 0.985 (0.959, 1.013) | 0.291 | 1.009 (0.981, 1.037) | 0.546 |
- The unadjusted model was not adjusted by any covariates. The adjusted model was fully adjusted for sex, age, race, educational attainment, BMI, smoking status, CVD, DM and hypertension. HR, hazard ratio; CI, confidence interval; P–t, P for trend; T1, the lowest tertile of Klotho level; T2, the moderate tertile of Klotho level; T3, the highest tertile of Klotho level; Ref, reference