Fig. 5

Relationship analysis of Klotho gene expression with fatty acid oxidation-related genes expression in CKD tubulointerstitium. A-F Comparative analysis of the expression of KL, PPARA, PPARGC1A, CPT1A, ACOX1 and ACOX2 in tubulointerstitium of Living Donors (n = 21) and CKD patients (n = 169) based on the Mann-Whitney test in GSE104954. G, H The heatmaps showed the correlation between each of genes (KL, PPARA, PPARGC1A, CPT1A, ACOX1 and ACOX2) in GSE104954 (CKD) and GSE108112 (CKD). The correlation was tested using Spearman correlation analysis. R represented correlation coefficient. *P < 0.05, **P < 0.01, ****P < 0.0001