Fig. 6
From: Crosstalk between m6A modification and autophagy in cancer
Role of m6A modification-mediated autophagy in head and neck tumors and leukemia, In head and neck tumours, m6a modification impacts the expression of target genes like TMA7, eIF4G1, and the stability of LncRNA ZFAS1. This modification also regulates autophagy levels and influences the progression of head and neck tumours as well as chemotherapy resistance. Similarly, in leukaemia, m6a modification affects the expression of target genes such as PTEN, TP53INP2, and the stability of LncRNA PSMA3-AS1. This modification also regulates the level of autophagy and affects the progression of leukaemia, particularly in terms of chemotherapy resistance