Fig. 3

Non-coding RNAs enriched in cardiac progenitor cell-derived exosomes promote heart regeneration after injury. CPC-derived exosomes which are rich in cardioprotective non-coding RNAs, including miRNAs and YRNAs, can be administered via intramyocardial injection or intracoronary infusion to the damaged heart and exert beneficial effects including reduction of fibrosis and infarct mass, reduced inflammation and cardiac hypertrophy and promotion of cardiomyocytes survival, angiogenesis and improvement of cardiac function Abbreviations: CPCs – cardiac progenitor cells, ncRNAs – non-coding RNAs (Created with BioRender.com)