Fig. 3
From: Therapeutic uses of oxytocin in stress-related neuropsychiatric disorders
The regulation of endogenous and exogenous OXT in stress-related neuropsychiatric diseases and the bidirectional influencing factors of oxytocin expression in the brain. In humans and animals, intranasal OXT administration and other stimuli, such as stress, maternal behavior, and sexual behavior et al., induce elevated OXT levels that project primarily to the prefrontal cortex, hippocampus, and amygdala. The interaction of OXT with OXTR increases stress resistance and improves stress-related neuropsychiatric diseases by regulating stress response, signaling pathways, neuronal excitability. Image created with Biorender.com