Fig. 1
LB disease signs, symptoms, diagnostics, and disease pathobiology. Disease signs and symptoms: Motor and non-motor symptoms are both included as operative processes leading to significant disability. Motor symptoms include bradykinesia, tremors, rigidity, and postural instability. The non-motor sings include, but are not limited to, depression, anxiety, hyposmia, and constipation. Neuroimaging methods: Tomographic acquisitions for neurodegenerative diseases include positron emission tomography (PET) scanning using 18F-fluorodeoxyglucose (18F-FDG) and 11C-IMA107 for DLB [31] and PD [32]. Pathology: The pathologies of synucleinopathies such as PD [33] and DLB [34] show depigmentation in the midbrain substantia nigra, Lewy neurites, and Lewy bodies (black arrows). The figure was created with BioRender.com. Images taken from publications or web pages were referenced in the figure caption