Skip to main content
Fig. 5 | Cell & Bioscience

Fig. 5

From: SHMT2 regulates esophageal cancer cell progression and immune Escape by mediating m6A modification of c-myc

Fig. 5

IGF2BP2 mediated c-myc m6A modification. A: Analysis of the correlation between IGF2BP1/2/3 and cmyc expression in EC; B: RT-qPCR was employed to analyze c-myc mRNA expression after knockdown of IGF2BP1/2/3; C: RIP assay was applied to verify the binding between IGF2BP2 and c-myc; D: SHMT2 affect the m6A modification of c-myc via IGF2BP2; E: Act D treatment; F: The expression of PD-L1 was detected after MYC overexpression or knockdown; G: The expression of PD-L1 was detected after SHMT2 overexpression or knockdown. *P < 0.05; **P < 0.01; ***P < 0.001

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us