Fig. 4
From: Single-cell analysis unveils activation of mast cells in colorectal cancer microenvironment
MC signature predicts better prognosis.
a. Kaplan-Meier disease-free survival curves grouped by MC signature genes (TPSAB1, TPSB2, CPA3, HPGDS, and MS4A2) in pan-cancer. b. Summary of the correlation between the expression of MC signature and overall survival (OS), disease-specific survival (DSS), disease-free interval (DFI), and progression-free interval (PFI) based on univariate Cox regression and Kaplan-Meier models. Red indicates factors that are detrimental to the prognosis of cancer patients, while green represents protective factors. Only p-values < 0.05 are displayed. c. The Kaplan-Meier overall survival curve of the MC signature in TCGA-CRC is shown, with the High-MC group and Low-MC group including patients with CRC who had MC signature expression in the top 30% and bottom 30%, respectively. d. Kaplan-Meier overall survival curve of MC signature in GSE39582