Fig. 5
From: c-Jun as a one-way valve at the naive to primed interface
c-Jun regulates chromatin accessibility in EpiSCs. A. Heatmap of sequence read density for ATAC-seq data in EpiSC-like and c- Jun knock out EpiSC-like signal on both open, primed open and naive open category defined in Fig. 3A, ranked by mean signal strength. Windows are centered on the ATAC-seq peak summit. Each row of the heatmap is a genomic locus. B. Pileup of ATAC-seq read density at the naive and primed peaks in EpiSClike and c-Jun Knock out EpiSC-like. C. Boxplot of the expression level for all genes with a TSS within 10 kb of an ATAC-seq peak in C1 ~ C4 loci. Data were converted to a log2 value for each gene. D. Volcano plot show the expression of the genes related to C3 peaks, mapping the high expressed genes in EpiSC-like (left) and high expressed genes in c- JunKO EpiSC-like (right)