Table 3 Concentration and conformational characteristics of Tau isoforms in AD cases
AD case | Total soluble tau | Insoluble total tau | Insoluble 3R tau | Insoluble 4R tau | 3R/4R tau ratio | ||||
|---|---|---|---|---|---|---|---|---|---|
Units | µg/ml | µg/ml | CDI D/N ratio | µg/ml | CDI D/N ratio | µg/ml | CDI D/N ratio | 3R (%) | 4R (%) |
AD 1 | 10.9 | 9.2 | 73.8 | 1.0 | 32.2 | 8.2 | 87.7 | 11.0 | 89.0 |
AD 2 | 8.3 | 4.1 | 50.1 | 0.6 | 17.1 | 3.6 | 72.6 | 13.8 | 86.2 |
AD 3 | 16.0 | 10.1 | 39.4 | 1.3 | 20.9 | 8.7 | 45.6 | 13.3 | 86.7 |
AD 4 | 9.5 | 5.1 | 49.5 | 0.6 | 24.2 | 4.5 | 57.5 | 11.8 | 88.2 |
AD 5 | 8.5 | 15.1 | 34.4 | 1.8 | 42.4 | 13.3 | 33.5 | 11.9 | 88.1 |
AD 6 | 5.4 | 1.3 | 13.6 | 0.3 | 6.0 | 1.0 | 21.1 | 21.8 | 78.2 |
Mo C57Bl | 15.1 | 0.094 | 0.7 | 0.001 | 0.8 | 0.093 | 0.7 | 1.6 | 98.4 |