Astaxanthin attenuates cognitive deficits in Alzheimer’s disease models by reducing oxidative stress via the SIRT1/PGC-1α signaling pathway

Table 2 Oxidative stress indexes in PC12 cells

Groups	ROS	MDA	SOD	GSH-px
Groups	(pmol/ml)	(nmol/ml)	(nU/ml)	(μmol/ml)
Control	89.65 ± 8.87	19.88 ± 2.73	58.13 ± 3.10	187.89 ± 6.91
Aβ	188.62 ± 10.07	37.54 ± 2.04	32.03 ± 6.04	96.30 ± 5.73
AST	78.88 ± 9.77	18.07 ± 3.47	68.72 ± 5.54	217.73 ± 10.14
Aβ + AST	126.05 ± 12.82	26.25 ± 4.33	49.94 ± 5.44	161.98 ± 7.99
Aβ + AST + NAM	153.84 ± 18.22	37.02 ± 3.18	39.81 ± 2.86	112.53 ± 8.61
Aβ + NAM	235.81 ± 22.14	50.36 ± 5.14	21.08 ± 3.17	84.41 ± 4.89

ISSN: 2045-3701