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Table 2 Assessment of liver fibrosis and NASH staging in pigs

From: Modelling porcine NAFLD by deletion of leptin and defining the role of AMPK in hepatic fibrosis

Type of Pig

NASH score

(12–22 months)

Fibrosis score

(22–35 months)

LEPTIN−/− -1

5.43

3.33

LEPTIN−/− -2

4.66

3.00

LEPTIN−/− -3

3.33

2.67

Mean ± SD

4.47 ± 0.86

3.00 ± 0.27

WT-1

0

0.67

WT-2

0.33

0.33

WT-3

0.67

0

Mean ± SD

0.33 ± 0.27

0.33 ± 0.27

  1. Brunt's and Scheuer scoring criteria were used to determine the stage of non-alcoholic liver inflammation and fibrosis in LEPTIN−/− and WT pigs