Fig. 3From: Mesenchymal stromal/stem cells and their extracellular vesicles in liver diseases: insights on their immunomodulatory roles and clinical applicationsStrategies to potentiate the therapeutic properties of MSCs. Several strategies have been proposed to optimize MSCs, which can be roughly divided into two categories: pre-treatment and gene modification. Pretreated or modifying MSCs using biomaterials or bioactive substances effectively facilitates their targeted delivery to sites of liver injury. MSCs, transplanted various routes, are recruited and reach the sites of liver injury, exerting hepatoprotective, regenerative, and anti-inflammatory effectsBack to article page