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Fig. 5 | Cell & Bioscience

Fig. 5

From: Menin orchestrates hepatic glucose and fatty acid uptake via deploying the cellular translocation of SIRT1 and PPARγ

Fig. 5

Histone deacetylase SIRT1 co-binds to the same promoter regions of Fabp genes being recruited by Menin. A. SIRT1 was found to interact with Menin in plain mouse hepatocytes via a Menin-IP assay. B. Representative ChIP-PCR results of the same promoter regions of Fabp3 (upper panel), Fabp4 (middle panel), and Fabp5 (lower panel) from anti-SIRT1 ChIPs in Menin over-expression (mMen1) and/or Menin-knockdown (siMen1) hepatocytes, as well as their corresponding control cells (Vector and Control)

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Cell & Bioscience

ISSN: 2045-3701

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