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Fig. 8 | Cell & Bioscience

Fig. 8

From: Post-translational modification of CDK1–STAT3 signaling by fisetin suppresses pancreatic cancer stem cell properties

Fig. 8

Fisetin inhibited CDK1-STAT3 signaling of PDAC in vivo. a Expressions of CDK1, p-STAT3 (Y705), CD44 and Sox2 in allograft tumors of KPC mice were examined by immunohistochemistry. Scale bars 200 μm. b Model indicating that regulation of epigenetic modification of CDK1–STAT3 signaling by fisetin leads to inhibition of cancer stemness properties in pancreatic cancer

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