Fig. 8
Inter-group distribution of the common PpGCs (CPpGCs) and full gene eccDNAs. A–B Histogram of all PpGCs in (A) control and (B) ALS samples. The vertical red line shows the position of the maximum of the distribution. C–D Heatmaps of the CPpGCs in (C) control and in (D) ALS as obtained with the democratic method. The color bars codify the value of the PpGCs in a log2 scale. The number of votes for each CPpGC is presented in tables to the right of the heatmaps. E Boolean heatmap of the entirety of whole coding genes embedded in eccDNA in any of the samples. Blue and red colors correspond to the presence and absence of full genes, respectively. In A-E: C, control samples; A, ALS samples