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Fig. 6 | Cell & Bioscience

Fig. 6

From: A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS

Fig. 6

Gene set enrichment analyses (GSEA) for the 225 DPpGCs up-regulated in ALS. A Functional categories and GSEA representing genes ranked according to their log2 (p-values). B Heatmap of all eccDNA embedded genes (DPpGCs and PpGCs) that are related to the adenylate cyclase modulating G protein signaling pathway found enriched by the GO term analyses given in (A). C Violin plot of the eccDNA-related genes assigned to the GO term ‘adenylate cyclase modulating G protein pathway’ in the control and ALS samples. The graph reveals a numerical enrichment of gene representants in ALS

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Cell & Bioscience

ISSN: 2045-3701

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