Fig. 2
From: Fluid shear stress induces a shift from glycolytic to amino acid pathway in human trophoblasts
FSS affects the trophoblast transcriptome. The volcano plot showing the significant changes in the transcriptome in differentiated BeWo cells, when cultured under flow, compared to cells cultured under static conditions. Red dots represent significantly differentially expressed genes with an adjusted p-value of ≤ 0.05 and an absolute log2 fold change of ≥ log2(1.5) (a). Dot plot showing the GSEA results for relevant gene ontology terms based on the comparison between flow and static conditions. The gene ratio represents the ratio of the number of core enriched genes among all genes. Dots are color-coded depending on their adjusted p-value. Size of the dots are presenting the number of core enriched genes in the respective gene sets (b). Presented data are based on triplicates, using three different cell passages each run and are provided in the source data set