Fig. 11

The expression levels and diagnostic role of plasma exosomal proteins validated in lung cancer patients and healthy controls. A, B The expression levels of plasma exosomal MUC5B and SELL were significantly elevated in lung cancer patients with BM. C The expression levels of plasma exosomal APOH were significantly upregulated in lung cancer patients with LM. D ROC curves assessed the diagnostic ability of plasma exosomal MUC5B and SELL in lung cancer patients with BM. E Plasma exosomal MUC5B and SELL combinations had the greatest AUC (0.808). F ROC curves assessed the diagnostic ability of plasma exosomal APOH in lung cancer patients with LM