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Fig. 10 | Cell & Bioscience

Fig. 10

From: Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis

Fig. 10

Diagnostic utility for the selected plasma-stemming exosome-based proteins in lung cancer patients with LM. A 10 soft clusters of LM. The horizontal axis indicates the initiation and progression of LM (HC, LA, and LM). The vertical axis indicates the expression of exosome-based proteins. B Nested analyses of LM versus LA and BM versus LM. 10 proteins belonged to the overlapping proteins of LM versus LA and BM versus LM, as well as to cluster A or B proteins. C ROC curves assessed the diagnoses capability for the 10 LM-distinct proteins. D The top three exosomal proteins combinations had the greatest AUC (0.927) for distinguishing between LM and LA, and BM patients

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