Fig. 5

Locomotion (distance moved) in Maze tests in ELP mice. ChR2-flfl and Avil-ChR2 mice were exposed to blue light in a chamber on postnatal day P1-P5 together with the Cre-negative blue-insensitive mother. Behavior was observed in adult female mice. The box/scatter plots show distances travelled during the 10 min observation period in the Open Field Test (OFT), Elevated Plus Maze (EPM), “3-chamber, 2-phases” test of Social Cognition & Memory and during a 30 min habituation period at ambient temperature in a Thermal Gradient Ring (TGR) maze. Mice were free to move or rest in the respective maze. The travel distances are readouts for locomotion, curiosity and activity. They were compared by unpaired, 2-tailed t-tests and did not differ between genotypes. Groups comprised n = 12 for ChR2-flfl and n = 14 for Avil-ChR2