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Fig. 3 | Cell & Bioscience

Fig. 3

From: Down-regulated FTO and ALKBH5 co-operatively activates FOXO signaling through m6A methylation modification in HK2 mRNA mediated by IGF2BP2 to enhance glycolysis in colorectal cancer

Fig. 3

ALKBH5 knockdown accelerates proliferation, migration, and invasion of CRC A The knockdown efficiency of ALKBH5 showed by western blot. B, C CCK-8 analysis of the effects of ALKBH5 knockdown on the CRC cell viability. D, E EdU analysis of the effects of ALKBH5 knockdown on the proliferation ability (magnification times, 200 ×). F, G Colony formation analysis of ALKBH5 knockdown on the colony formation ability. H–J Transwell of ALKBH5 knockdown on the CRC cell migration and invasion (magnification times, 100 ×). **p < 0.01; ***p < 0.001

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Cell & Bioscience

ISSN: 2045-3701

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