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Fig. 1 | Cell & Bioscience

Fig. 1

From: Down-regulated FTO and ALKBH5 co-operatively activates FOXO signaling through m6A methylation modification in HK2 mRNA mediated by IGF2BP2 to enhance glycolysis in colorectal cancer

Fig. 1

The expression of FTO and ALKBH5 in human colorectal cancer. A Representative images of IHC staining FTO and ALKBH5 in TMAs. B, C The positive percentage of FTO and ALKBH5 in CRC tissues and normal tissues. D Western blot analysis of FTO and ALKBH5 expression in CRC cancer cells and NCM460 cells. E The expression of FTO and ALKBH5 in representative CRC tissues and adjacent normal tissues was indicated by western blot. F The expression of FTO and ALKBH5 in obesity CRC group and normal weight CRC groups. G Western blot showing FTO and ALKBH5 expression in CRC cells treated with palmitic acid in different concentrations for 24 h. **p < 0.01

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