Fig. 5
The in vivo expressions of SARS-CoV-2 mAbs with engineered MSCs delivery. (a) Schematic overview of the animal experiment. (b) Concentrations of mAbs in serum, n = 4. (c) Bio-imaging of mice body at day1 and mice were sacrificed at day1 post engineered MSCs administration and dissected organs were imaged (n = 3). Lu, lung; K, kidney; H, heart; S, spleen; Li, liver; I, intestines. (d) The lung tissues collected at 1 day and 3 days after the administration of engineered MSCs and SARS-CoV-2 mAbs were subjected to IFAs analysis for the expressions of SARS-CoV-2 mAbs using PE conjugated goat anti-human IgG (H + L). Bar scle = 50 μm or 25 μm. (n = 4 mice per group)