Fig. 7From: Rhox6 regulates the expression of distinct target genes to mediate mouse PGCLC formation and ESC self-renewalSchematic diagram of the role of Rhox6 in ESC maintenance and PGCLC specification. Overexpression of Rhox6 induces Nanos3 expression to facilitate the formation of PGCLCs derived from EpiLCs. On the other hand, downregulation of Rhox6 stimulates Tbx3 expression to favor maintenance of mESC stemnessBack to article page