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Table 2 Association of identified markers with chemoresistance

From: Exploring the cellular and molecular differences between ovarian clear cell carcinoma and high-grade serous carcinoma using single-cell RNA sequencing and GEO gene expression signatures

 

OCCC

HGSC

 

PR (n = 15)

PS (n = 113)

p value

PR (n = 2)

PS (n = 79)

p value

AOC1

6 (40.0%)

74 (65.5%)

0.055

0 (0)

9 (11.4%)

1.000

GPX3

4 (26.7%)

67 (59.3%)

0.017a

0 (0)

3 (3.8%)

1.000

LEFTY1

14 (93.3%)

105 (92.9%)

1.000

2 (100.0%)

36 (45.6%)

0.217

S100A2

1 (6.7%)

3 (2.7%)

0.396

1 (50.0%)

26 (32.9%)

1.000

CRABP2

7 (46.7%)

34 (30.1%)

0.318

2 (100.0%)

72 (91.1%)

1.000

WFDC2

1 (6.7%)

31 (27.2%)

0.158

2 (100.0%)

54 (68.4%)

1.000

  1. Values indicate the number of patients for whom samples showed high immunohistochemical staining (percentages)
  2. PR: platinum-resistant; PS: platinum-sensitive
  3. a: statistically significant