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Fig. 1 | Cell & Bioscience

Fig. 1

From: The interwoven fibril-like structure of amyloid-beta plaques in mouse brain tissue visualized using super-resolution STED microscopy

Fig. 1

Super-resolution STED microscopy and TEM images of in vitro formed Aβ40 aggregates. A Super-resolution STED microscopy image of in vitro formed Aβ40 aggregates rendered visible using 1C3-DyLight633. Scale bar 2 μm. B Fluorescence intensity profile along the fibril highlighted by yellow arrows showing a fibril diameter of 44 nm. C The diffraction-limited CLSM image of Aβ40 aggregates shown in A. Scale bar 2 μm. D Negatively stained TEM image of in vitro formed Aβ40 aggregates showing single-threaded filaments (7 ± 2) nm and twisted two-filament fibers (14 ± 1) nm. Scale bar 100 nm

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Cell & Bioscience

ISSN: 2045-3701

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