Fig. 1

MCT induce HSOS-like liver injury in rats. A, B Serum ALT and AST activity. C The typical macroscopic (upper) and histological (down) observations of MCT-induced liver injury. D The % area of necrosis quantified in a low power field (100 ×). E The total HSOS score. F The protein expression of MMP-9 in liver tissues. GAPDH was used as a loading control. Data were shown as mean ± SEM. N = 4. *p < 0.05, **p < 0.01. MCT, monocrotaline; HSOS, hepatic sinus obstruction syndrome; ALT, alanine aminotransferase; AST, aspartate aminotransferase; MMP-9, matrix metalloproteinase-9; GPADH, glyceraldehyde-3phosphate dehydrogenase