Table 2 Summary of the functional features of the 12 Fra-1-bound TGFB2 enhancers
Enhancer | Requirement of Fra-1 | Requirement of p300/CBP | Requirement of KAT activity | Enhancer category |
|---|---|---|---|---|
 + 32 | Yes | Yes | Yes | Dependent on Fra-1 and p300/CBP KAT activity |
 + 115 | Yes | Yes | Yes | Dependent on Fra-1 and p300/CBP KAT activity |
 + 118 | Yes | Yes | Yes | Dependent on Fra-1 and p300/CBP KAT activity |
 + 136 | Yes | Yes | No | Dependent on Fra-1 and p300/CBP but not on its KAT activity |
 + 151 | Yes | Yes | Yes | Dependent on Fra-1 and p300/CBP KAT activity |
 + 240 | Yes | Yes | Yes | Dependent on Fra-1 and p300/CBP KAT activity |
 + 314 | Yes | Yes | Yes | Dependent on Fra-1 and p300/CBP KAT activity |
 + 315 | Yes | Yes | Yes | Dependent on Fra-1 and p300/CBP KAT activity |
 + 360 | No | Yes | Yes | Fra-1-independent but dependent on p300/CBP KAT activity |
 + 744 | Yes | Yes | No | Dependent on Fra-1 and p300/CBP but not on its KAT activity |
 + 980 | Yes | No | No | Dependent on Fra-1 but p300/CBP-independent |
 + 1426 | No | Yes | No | Fra-1-independent, dependent on p300/CBP but not on its KAT activity |