Fig. 5
From: Fanca deficiency is associated with alterations in osteoclastogenesis that are rescued by TNFα
NF-kB status in OCs from WT and Fanca−/− mice with or without TNFα. A Representative Western blot showing NF-kB canonical and noncanonical signaling pathway protein levels 4 days postdifferentiation in OCs from WT and Fanca−/− mice with or without TNFα. β-Actin was used as a loading control. B Quantification of data concerning P-p65, p105, p50 and RelB 4 days postdifferentiation in OCs from WT and Fanca−/− mice left untreated (NT) or treated with TNFα. Blue bars are for WT and red bars for Fanca-/- OCs. Data are shown as the mean ± SEM. Each small circle represents an individual mouse. Statistical analysis was performed by t tests: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001