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Fig. 6 | Cell & Bioscience

Fig. 6

From: Serine protease PRSS56, a novel cancer-testis antigen activated by DNA hypomethylation, promotes colorectal and gastric cancer progression via PI3K/AKT axis

Fig. 6

PRSS56 overexpression promoted tumor progression in GC and CRC. (A) The GC and CRC cell lines stably overexpressing PRSS56 were constructed by lentivirus method. (B, C) The overexpression efficiency of PRSS56 in the relevant cell lines was measured by the qRT-PCR and western blotting assays. (D) Overexpression of PRSS56 promoted tumor cell proliferation in GC and CRC. (E, F) Overexpression of PRSS56 promoted tumor cell migration at indicated hours (24 and 48 h) in GC and CRC. (G, H) Overexpression of PRSS56 promoted tumor cell invasion in GC and CRC. **P < 0.01

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