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Fig. 5 | Cell & Bioscience

Fig. 5

From: Serine protease PRSS56, a novel cancer-testis antigen activated by DNA hypomethylation, promotes colorectal and gastric cancer progression via PI3K/AKT axis

Fig. 5

The DNA methylation level of PRSS56 gene in GC and CRC. (A) The DNA methylation level (β value) of PRSS56 in HCT116 cells treated with 5-Aza-CdR was analyzed using GSE68344 dataset. (B) The DNA methylation level (β value) of PRSS56 in wildtype (WT) and DNMT1 and DNMT3B double KO (DKO) HCT116 cells treated with 5-Aza-CdR was analyzed using GSE29290 dataset. (C, D) The DNA methylation level (β value) of PRSS56 in normal and tumor tissues in GC and CRC patients using GSE79740 and GSE85464 dataset

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Cell & Bioscience

ISSN: 2045-3701

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