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Fig. 5 | Cell & Bioscience

Fig. 5

From: TRIM67 alleviates cerebral ischemia‒reperfusion injury by protecting neurons and inhibiting neuroinflammation via targeting IκBα for K63-linked polyubiquitination

Fig. 5

TRIM67 upregulation reduces postischemic neuroinflammation. RT-qPCR and ELISA were used to determine the mRNA (A) and protein (B) expression of IL-1β, IL-6, TNF-α, CXCL1, and CCL2 in peri-infarct cortex, hippocampus and striatum brain tissues (n = 5). C western blotting investigation of IL-1β, IL-6, and TNF-α expression in peri-infarct cortex, hippocampus and striatum brain tissues. D Quantitative analysis of inflammatory cytokines is shown in C (n = 5). The mean ± SD are displayed for all data. **p < 0.01, ***p < 0.001 and ****p < 0.0001

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