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Fig. 3 | Cell & Bioscience

Fig. 3

From: TRIM67 alleviates cerebral ischemia‒reperfusion injury by protecting neurons and inhibiting neuroinflammation via targeting IκBα for K63-linked polyubiquitination

Fig. 3

TRIM67 upregulation preserves cognitive function following cerebral ischemia‒reperfusion injury in mice. A and B Morris water maze (MWM) swimming traces of mice in latency and probe trials. C and D In the MWM tests, escape latency to uncover the hidden platform in the latency trial. E The number of times the mice passed the target platform position on Day 7 during the probe trials. F Time spent in the target quadrant in the probe trial on Day 7. G Preference index for the novel object in the novel object recognition (NOR) task. The discrimination index was recorded in the test phase. n = 6–8 mice per group. The mean ± SD are displayed for all data. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001

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Cell & Bioscience

ISSN: 2045-3701

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