Fig. 5

Decreased inhibitory synaptic responses and hyperactivity of M/Ts in OB of 6-month-old SNCA-A53T mice. a Representative images showing mEPSCs of M/Ts in OB. b-c Cumulative curves (b) and quantification (c) of mEPSCs frequency of M/Ts in OB of WT and A53T mice (n = 4 for each group). d-e Cumulative curves (d) and quantification (e) of mEPSCs amplitude of M/Ts in OB of WT and A53T mice (n = 4 for each group). f Representative images showing mIPSCs of M/Ts in OB. g-h Cumulative curves (g) and quantification (h) of mIPSCs frequency of M/Ts in OB of WT and A53T mice (n = 4 for each group). i-j Cumulative curves (i) and quantification (j) of mIPSCs amplitude of M/Ts in OB of WT and A53T mice (n = 4 for each group). k Representative images showing sAP of M/Ts in OB. l Quantitative analysis of normalized sAP frequency of M/Ts in OB of WT and A53T mice (n = 4 for each group). Data are presented as mean ± SEM. *p < 0.05; **p < 0.01; n.s., not significant