Fig. 1

Impaired olfactory behaviors of 6-month-old SNCA-A53T mice. a Schematic diagram illustrating the buried and visual food tests. b-e Quantification of latency to find a food pellet buried (b, d) or on the surface (c, e) of bedding in 3-month-old and 6-month-old WT and A53T mice (n = 12 for each group). f Schematic diagram of olfactory preference/avoidance test. g-h Percentage of time spent on sniffing the odor area containing oil, PB, and TMT, in 3-month-old (g) and 6-month-old (h) WT and A53T mice (n = 12 for each group). i Schematic diagram showing the olfactory discrimination test. j-k Percentage of correct olfactory discrimination per trial session in 3-month-old (j) and 6-month-old (k) WT and A53T mice (n = 12 for each group). Data are presented as mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; n.s., not significant